SCHEMBL444940

SCHEMBL444940

CO[Si](CCCSSSSc1nc2ccccc2s1)(OC)OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 3/20 0.52
ALDH1A1 P00352 4/20 0.50
HSD17B10 Q99714 2/20 0.50
HPGD P15428 2/20 0.50
PDK1 Q15118 2/20 0.50
ADRA2A P08913 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
DRD2 P14416 1/20 0.50
ALOX15 P16050 1/20 0.50
ADRA2B P18089 1/20 0.50
ADRA2C P18825 1/20 0.50
DRD1 P21728 1/20 0.50
MC5R P33032 1/20 0.50
OPRM1 P35372 1/20 0.50
DRD3 P35462 1/20 0.50
OPRK1 P41145 1/20 0.50
CCR2 P41597 1/20 0.50
HTR6 P50406 1/20 0.50
SLC6A3 Q01959 1/20 0.50
TDP1 Q9NUW8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29651869 1.00 FBP1 (0.52) FBP1ALDH1A1HSD17B10HPGDPDK1
SCHEMBL8826557 0.99 FBP1 (0.51) FBP1ALDH1A1HSD17B10HPGDPDK1
SCHEMBL8826523 0.99 FBP1 (0.51) FBP1ALDH1A1HSD17B10HPGDPDK1
SCHEMBL8826858 0.99 FBP1 (0.51) FBP1ALDH1A1HSD17B10HPGDPDK1
SCHEMBL8826656 0.99 FBP1 (0.51) FBP1ALDH1A1HSD17B10HPGDPDK1
SCHEMBL8826640 0.96 FBP1 (0.51) FBP1ALDH1A1HSD17B10HPGDPDK1
SCHEMBL8826688 0.96 FBP1 (0.53) FBP1ALDH1A1HSD17B10HPGDPDK1
SCHEMBL8827007 0.95 FBP1 (0.50) FBP1ALDH1A1HSD17B10HPGDPDK1
SCHEMBL8826499 0.95 FBP1 (0.50) FBP1ALDH1A1HSD17B10HPGDPDK1
SCHEMBL8826497 0.95 FBP1 (0.50) FBP1ALDH1A1HSD17B10HPGDPDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1404 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11852647-B2 Method for predicting the rubber reinforcing effect of organic-inorganic composite for rubber reinforcement LG CHEM, LTD. 2023-12-26 US claimed
CN-109565058-B Electrode comprising organofunctional metal oxide, method for producing same, membrane electrode assembly, and fuel cell comprising same 可隆工业株式会社 2022-07-12 CN claimed
EP-3534144-B1 METHOD FOR PREDICTING RUBBER REINFORCEMENT EFFECT OF ORGANIC-INORGANIC COMPOSITE FOR RUBBER REINFORCEMENT LG CHEMICAL LTD (KR) 2021-12-22 EP claimed
US-11059956-B2 Organic-inorganic composite for rubber reinforcement, method for preparing the same, and rubber composition for tires comprising the same LG CHEM, LTD. (KR) 2021-07-13 US claimed
EP-3533825-B1 ORGANIC-INORGANIC COMPOSITE FOR REINFORCING RUBBER, PREPARATION METHOD THEREFOR, AND TIRE RUBBER COMPOSITION COMPRISING SAME LG CHEMICAL LTD (KR) 2020-10-21 EP claimed
US-20200131341-A1 Organic-Inorganic Composite for Rubber Reinforcement, Method for Preparing the Same, and Rubber Composition for Tires Comprising the Same LG CHEM, LTD. (KR) 2020-04-30 US claimed
US-20190310176-A1 Method for Predicting the Rubber Reinforcing Effect of Organic-Inorganic Composite for Rubber Reinforcement LG CHEM, LTD. (KR) 2019-10-10 US claimed
EP-3533825-A1 ORGANIC-INORGANIC COMPOSITE FOR REINFORCING RUBBER, PREPARATION METHOD THEREFOR, AND TIRE RUBBER COMPOSITION COMPRISING SAME LG Chem, Ltd. (KR) 2019-09-04 EP claimed
EP-3534144-A2 METHOD FOR PREDICTING RUBBER REINFORCEMENT EFFECT OF ORGANIC-INORGANIC COMPOSITE FOR RUBBER REINFORCEMENT LG Chem, Ltd. (KR) 2019-09-04 EP claimed
EP-3196233-B1 METHOD FOR PRODUCING RUBBER COMPOSITION FOR TIRE, AND TIRE SUMITOMO RUBBER IND (JP) 2019-07-24 EP claimed
US-12630696-B2 Rubber composition, and tire ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-05-19 US disclosed
CN-119768462-B Rubber composition 横滨橡胶株式会社 2026-05-15 CN disclosed
CN-122055426-A Sealing member 住友理工株式会社 2026-05-15 CN disclosed
EP-4737489-A1 CATALYST COMPOSITION PREPARATION METHOD AND CONJUGATED DIENE-BASED POLYMER PREPARATION METHOD LG CHEM, LTD. (KR) 2026-05-06 EP disclosed
EP-4349616-B1 RUBBER COMPOSITION FOR TIRE, TREAD RUBBER, AND TIRE BRIDGESTONE CORP (JP) 2026-05-06 EP disclosed
EP-0882738-A1 DIENE RUBBER, PROCESS FOR PRODUCING THE RUBBER AND RUBBER COMPOSITION CONTAINING THE SAME NIPPON ZEON CO., LTD. (JP) 1998-12-09 EP disclosed
EP-0870786-A1 DIENE RUBBER, PROCESS FOR THE PREPARATION OF THE SAME AND COMPOSITION CONTAINING THE SAME NIPPON ZEON CO., LTD. (JP) 1998-10-14 EP disclosed
EP-0864606-A1 RUBBER COMPOSITION NIPPON ZEON CO., LTD. (JP) 1998-09-16 EP disclosed
EP-0864592-A1 DIENE RUBBER NIPPON ZEON CO., LTD. (JP) 1998-09-16 EP disclosed
US-5684172-A REACTING BENZOTHIAZOLYL MORPHOLINYL DISULFIDE WITH A MERCAPTOALKYLALKOXYSILANE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630696-B2 Rubber composition, and tire THRB, RIF1, THRA FBP1 3128/4885ALDH1A1 3448/4885HSD17B10 1805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.