Phthalic Anhydride

Phthalic Anhydride

SCHEMBL4449505

C=C(C)C(=O)OCCO.O=C1OC(=O)c2ccccc21

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
GLA P06280 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 2/20 0.42
ALOX15 P16050 1/20 0.42
THRB P10828 1/20 0.40
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TSHR P16473 4/20 0.39
TDP2 O95551 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
MAPK1 P28482 1/20 0.35
ELANE P08246 1/20 0.35
TARBP2 Q15633 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Anhydride SCHEMBL2460960 0.92 THRB (0.46) ALDH1A1GLAKMT2ATDP1ALOX15
Phthalic Anhydride SCHEMBL2460972 0.82 ALOX15 (0.42) ALDH1A1GLAKMT2ATDP1ALOX15
SCHEMBL25293586 0.80 THRB (0.41) ALDH1A1TDP1THRBPOLBAPEX1
Benzene SCHEMBL28116485 0.80 THRB (0.53) ALDH1A1TDP1THRBPOLBAPEX1
Maleic Anhydride SCHEMBL7612632 0.80 THRB (0.43) ALDH1A1TDP1THRBPOLBAPEX1
Phenol SCHEMBL28875314 0.80 TDP1 (0.46) ALDH1A1GLATDP1THRBPOLB
Biphenyl SCHEMBL8063223 0.80 POLB (0.46) ALDH1A1TDP1THRBPOLBAPEX1
Toluene SCHEMBL11225215 0.80 POLB (0.46) ALDH1A1KMT2ATDP1THRBPOLB
SCHEMBL8063412 0.78 POLB (0.40) ALDH1A1KMT2ATDP1THRBPOLB
Diphenylether SCHEMBL8065399 0.78 POLB (0.48) ALDH1A1TDP1THRBPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1189994-B1 OIL SOLUBLE RADIATION CURABLE METAL-CONTAINING COMPOUNDS AND COMPOSITIONS SARTOMER CO INC (US) 2009-03-18 EP disclosed
US-6399672-B1 OIL SOLUBLE UNSATURATED COMPOUNDS AND PHOTOINITIATORS SARTOMER TECHNOLOGIES CO., INC. 2002-06-04 US disclosed
EP-1189994-A2 OIL SOLUBLE RADIATION CURABLE METAL-CONTAINING COMPOUNDS AND COMPOSITIONS SARTOMER COMPANY, INC. (US) 2002-03-27 EP disclosed
WO-2000075241-A2 OIL SOLUBLE RADIATION CURABLE METAL-CONTAINING COMPOUNDS AND COMPOSITIONS SARTOMER COMPANY, INC. (US) 2000-12-14 WO disclosed