Phthalic Anhydride

Phthalic Anhydride

SCHEMBL2460972

C=C(C)C(=O)O.O=C1OC(=O)c2ccccc21.OCCOCCO

nearest known ligand 0.42

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Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 9/20 0.40
KMT2A Q03164 3/20 0.40
GLA P06280 1/20 0.40
HSD17B10 Q99714 1/20 0.40
KDM4E B2RXH2 5/20 0.39
SMN1; SMN2 Q16637 3/20 0.36
USP2 O75604 1/20 0.36
MEN1 O00255 2/20 0.36
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Anhydride SCHEMBL2460960 0.86 THRB (0.46) ALOX15TDP1ALDH1A1KMT2AGLA
Phthalic Anhydride SCHEMBL185274 0.85 ALOX15 (0.58) ALOX15TDP1ALDH1A1KMT2AGLA
Phthalic Anhydride SCHEMBL31125295 0.85 TDP1 (0.58) ALOX15TDP1ALDH1A1KMT2AGLA
Phthalic Anhydride SCHEMBL28323891 0.84 ALOX15 (0.56) ALOX15TDP1ALDH1A1KMT2AGLA
Phthalic Anhydride SCHEMBL4449505 0.82 ALDH1A1 (0.46) ALOX15TDP1ALDH1A1KMT2AGLA
Phthalic Anhydride SCHEMBL28952608 0.80 ALOX15 (0.44) ALOX15TDP1ALDH1A1SMN1; SMN2MAPK1
Di(Hydroxyethyl)Ether SCHEMBL28258879 0.80 TSHR (0.43) ALDH1A1KMT2AKDM4ESMN1; SMN2MEN1
Phthalic Acid SCHEMBL477950 0.80 ALDH1A1 (0.47) ALOX15TDP1ALDH1A1KMT2AHSD17B10
Phthalic Acid SCHEMBL1398209 0.80 ALDH1A1 (0.47) ALOX15TDP1ALDH1A1KMT2AHSD17B10
Maleic Anhydride SCHEMBL27950129 0.80 TSHR (0.33) KMT2AMEN1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8476824-B2 Active matrix organic electroluminescent device and method of manufacture thereof UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA (CN) 2013-07-02 US disclosed
US-8278820-B2 Active matrix organic electroluminescent device and method of manufacture thereof University of Electric Sience and Technology of China (CN) 2012-10-02 US disclosed
US-20120164762-A1 Active matrix organic electroluminescent device and method of manufacture thereof UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA 2012-06-28 US disclosed
US-20110221331-A1 Active matrix organic electroluminescent device and method of manufacture thereof UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA 2011-09-15 US disclosed