Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 2/20 | 0.36 |
| ▸ | PGK2 | P07205 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708602 | 0.81 | MAPK1 (0.50) | ESR1ESR2HDAC4HDAC2HDAC8 | |
| SCHEMBL2341327 | 0.80 | ESR1 (0.41) | ESR1ESR2HDAC4HDAC2HDAC8 | |
| SCHEMBL25786332 | 0.80 | KIF11 (0.47) | KIF11TAAR1ACHE | |
| Bromide SCHEMBL8601711 | 0.79 | MAPK1 (0.48) | ESR1ESR2HDAC4HDAC2HDAC8 | |
| SCHEMBL129151 | 0.78 | HDAC8 (0.56) | ESR1ESR2HDAC4HDAC2HDAC8 | |
| SCHEMBL2241265 | 0.75 | ESR1 (0.46) | ESR1ESR2HDAC4HDAC2HDAC8 | |
| Water SCHEMBL29289408 | 0.75 | HDAC8 (0.54) | ESR1ESR2HDAC4HDAC2HDAC8 | |
| SCHEMBL25505057 | 0.75 | HDAC8 (0.44) | ESR1ESR2HDAC4HDAC2HDAC8 | |
| SCHEMBL23026518 | 0.73 | ESR1 (0.44) | ESR1ESR2HDAC4HDAC2HDAC8 | |
| SCHEMBL5450074 | 0.73 | ESR1 (0.44) | ESR1ESR2HDAC4HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101448773-B | Metal complexes for use in the carbonylation of ethylenically unsaturated compounds | LUCITE INT UK LTD | 2015-02-11 | — | — | CN | disclosed |
| US-8445711-B2 | Metal complexes | LUCITE INTERNATIONAL UK LIMITED (GB) | 2013-05-21 | — | — | US | disclosed |
| US-20090312561-A1 | METAL COMPLEXES | LUCITE INTERNATIONAL UK LIMITED (GB) | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312561-A1 | METAL COMPLEXES | MLX, PICALM, AP2M1 | ESR1 3034/4885ESR2 3317/4885HDAC4 3138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.