Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 2/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4449988 | 1.00 | TRPV1 (0.46) | TRPV1NPC1RAB9AALDH1A1TLR7 | |
| SCHEMBL14024210 | 0.88 | TRPV1 (0.39) | TRPV1NPC1RAB9AALDH1A1TLR7 | |
| SCHEMBL4448522 | 0.81 | L3MBTL1 (0.54) | NPC1RAB9AALDH1A1HDAC1 | |
| SCHEMBL4448518 | 0.81 | L3MBTL1 (0.54) | NPC1RAB9AALDH1A1HDAC1 | |
| SCHEMBL4445027 | 0.81 | HPGDS (0.59) | NPC1RAB9AALDH1A1GAACYP3A4 | |
| SCHEMBL4445032 | 0.81 | HPGDS (0.59) | NPC1RAB9AALDH1A1GAACYP3A4 | |
| SCHEMBL4456906 | 0.80 | KMT2A (0.49) | NPC1ALDH1A1HDAC1CYP3A4 | |
| SCHEMBL4456908 | 0.80 | KMT2A (0.49) | NPC1ALDH1A1HDAC1CYP3A4 | |
| SCHEMBL4456912 | 0.80 | KDM4E (0.55) | NPC1ALDH1A1GAAGPR139 | |
| SCHEMBL4456911 | 0.80 | KDM4E (0.55) | NPC1ALDH1A1GAAGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012010-A1 | Amino acid derivatives as calcium channel blockers | NEUROMED PHRAMACEUTICALS LTD. (CA) | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012010-A1 | Amino acid derivatives as calcium channel blockers | CACNA1G, CACNA1H, CACNA1I | TRPV1 40/4885NPC1 2098/4885RAB9A 1242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.