Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.54 |
| ▸ | NPC1 | O15118 | 11/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4450024 | 1.00 | RAB9A (0.54) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13783957 | 1.00 | RAB9A (0.54) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4460386 | 0.86 | MAPT (0.61) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4460394 | 0.86 | MAPT (0.61) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4330504 | 0.80 | MTOR (0.48) | — | |
| SCHEMBL4454924 | 0.79 | KMT2A (0.39) | RAB9ANPC1KMT2AMEN1TP53 | |
| SCHEMBL4454929 | 0.79 | KMT2A (0.39) | RAB9ANPC1KMT2AMEN1TP53 | |
| SCHEMBL13784017 | 0.79 | KMT2A (0.39) | RAB9ANPC1KMT2AMEN1TP53 | |
| SCHEMBL13783979 | 0.78 | CASP3 (0.43) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4451601 | 0.78 | CASP3 (0.43) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | claimed |
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |