Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13784017 | 1.00 | KMT2A (0.39) | KMT2ANPC1RAB9AMEN1SHMT2 | |
| SCHEMBL4454929 | 1.00 | KMT2A (0.39) | KMT2ANPC1RAB9AMEN1SHMT2 | |
| SCHEMBL4450024 | 0.79 | RAB9A (0.54) | KMT2ANPC1RAB9AMEN1TRPV1 | |
| SCHEMBL4450022 | 0.79 | RAB9A (0.54) | KMT2ANPC1RAB9AMEN1TRPV1 | |
| SCHEMBL13783957 | 0.79 | RAB9A (0.54) | KMT2ANPC1RAB9AMEN1TRPV1 | |
| SCHEMBL13783979 | 0.74 | CASP3 (0.43) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL4451608 | 0.74 | CASP3 (0.43) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL4451601 | 0.74 | CASP3 (0.43) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL4462424 | 0.74 | KDM4E (0.47) | KMT2ANPC1RAB9AMEN1TRPV1 | |
| SCHEMBL4462419 | 0.74 | KDM4E (0.47) | KMT2ANPC1RAB9AMEN1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | claimed |
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |