Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4083462 | 0.78 | CA1 (0.43) | KMT2AMMP1GAAMMP12ALDH1A1 | |
| SCHEMBL13901918 | 0.70 | CA1 (0.42) | KMT2AGAAPLAUALDH1A1KDM4E | |
| SCHEMBL13901598 | 0.70 | CA1 (0.41) | KMT2AGAAAPEX1PLAUALDH1A1 | |
| SCHEMBL4088650 | 0.70 | POLB (0.40) | KMT2AGAAALDH1A1KDM4ETDP1 | |
| SCHEMBL15787094 | 0.66 | APEX1 (0.62) | KMT2AMMP1GAAMMP12APEX1 | |
| SCHEMBL6438335 | 0.62 | ALDH1A1 (0.69) | KMT2AMMP1GAAMMP12APEX1 | |
| SCHEMBL3905853 | 0.60 | APEX1 (0.57) | KMT2AMMP1GAAMMP12APEX1 | |
| SCHEMBL359770 | 0.60 | MMP1 (0.79) | KMT2AMMP1GAAMMP12APEX1 | |
| SCHEMBL4017916 | 0.60 | SMN1; SMN2 (0.58) | KMT2AGAAALDH1A1KDM4ETDP1 | |
| SCHEMBL6419794 | 0.60 | GAA (0.63) | KMT2AMMP1GAAMMP12LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011850-A2 | NOVEL THERAPEUTIC COMPOUNDS | ABBOTT LABORATORIES (US) | 2009-01-22 | — | — | WO | disclosed |