SCHEMBL4450110

SCHEMBL4450110

C=CCCc1ccc(-c2ccc(C=C)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
TSHR P16473 1/20 0.36
HRH3 Q9Y5N1 3/20 0.34
MEN1 O00255 1/20 0.34
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
PIK3CG P48736 1/20 0.32
MAOB P27338 2/20 0.31
HDAC8 Q9BY41 1/20 0.31
GPR52 Q9Y2T5 1/20 0.31
FFAR1 O14842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346414 0.94 ALDH1A1 (0.52) ALDH1A1TSHRMEN1TP53MAPT
SCHEMBL8854472 0.89 HRH3 (0.41) ALDH1A1TSHRHRH3TP53MAOB
SCHEMBL4442399 0.88 ALDH1A1 (0.42) ALDH1A1TSHRHRH3MEN1TP53
SCHEMBL9004481 0.88 HDAC2 (0.36) HRH3MAOBHDAC8GPR52FFAR1
SCHEMBL9004485 0.88 HDAC2 (0.36) HRH3MAOBHDAC8GPR52FFAR1
SCHEMBL4444152 0.82 PTGS2 (0.40) ALDH1A1TSHRGPR52
SCHEMBL9004469 0.82 GFER (0.36) ALDH1A1TSHRMEN1TP53MAPT
SCHEMBL10639413 0.81 FFAR1 (0.48) ALDH1A1TSHRGPR52FFAR1
SCHEMBL8857437 0.81 ALDH1A1 (0.45) ALDH1A1TSHRHRH3MEN1TP53
SCHEMBL3670690 0.81 ALDH1A1 (0.48) ALDH1A1TSHRMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5418276-A Styrene copolymer, syndiotactic, heat resistance, chemical resistance IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US claimed
US-5362814-A Styrene polymers with olefin monomers and diolefin monomers for impact strength in molding materials IDEMITSU KOSAN CO., LTD. (JP) 1994-11-08 US claimed
EP-1408080-B1 POLYOLEFIN RESIN COMPOSITION IDEMITSU KOSAN CO (JP) 2012-12-26 EP disclosed
US-7531605-B2 Process for producing polyolefin resin composition and polypropylene composition IDEMITSU KOSAN CO., LTD. (JP) 2009-05-12 US disclosed
EP-1375538-B1 PROCESS FOR PRODUCING POLYOLEFIN RESIN COMPOSITION AND POLYPROPYLENE COMPOSITION IDEMITSU KOSAN CO (JP) 2008-01-09 EP disclosed
US-7193013-B2 Polyolefin resin composition IDEMITSU KOSAN CO. LTD. (JP) 2007-03-20 US disclosed
US-7189788-B2 Polyolefin resin composition IDEMITSU KOSAN CO. LTD. (JP) 2007-03-13 US disclosed
EP-1367093-B1 POLYOLEFIN RESIN COMPOSITION IDEMITSU KOSAN CO (JP) 2005-12-14 EP disclosed
US-20040176520-A1 Polyolefin resin composition IDEMITSU KOSAN CO. LTD. (JP) 2004-09-09 US disclosed
US-20040106738-A1 Process for producing polyolefin resin composition and polypropylene composition IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-06-03 US disclosed
US-20040072950-A1 High strength, chemical resistance, weatherproofing molding materials; graft polymers IDEMITSU KOSAN CO. LTD. (JP) 2004-04-15 US disclosed
EP-0667359-B1 OLEFIN COPOLYMERS AND PROCESS FOR PRODUCING THE SAME IDEMITSU KOSAN CO (JP) 2004-03-31 EP disclosed
EP-1375538-A1 PROCESS FOR PRODUCING POLYOLEFIN RESIN COMPOSITION AND POLYPROPYLENE COMPOSITION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-01-02 EP disclosed
EP-1367093-A1 POLYOLEFIN RESIN COMPOSITION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-12-03 EP disclosed
EP-0559108-B1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN CO (JP) 1997-05-28 EP disclosed
US-5608009-A OLEFIN-DIOLEFIN GRAFT POLYMER IDEMITSU KOSAN CO., LTD. (JP) 1997-03-04 US disclosed
EP-0667359-A1 OLEFIN COPOLYMERS AND PROCESS FOR PRODUCING THE SAME IDEMITSU KOSAN COMPANY LIMITED (JP) 1995-08-16 EP disclosed
US-5418276-A Styrene copolymer, syndiotactic, heat resistance, chemical resistance IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US disclosed
US-5362814-A Styrene polymers with olefin monomers and diolefin monomers for impact strength in molding materials IDEMITSU KOSAN CO., LTD. (JP) 1994-11-08 US disclosed
EP-0559108-A1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-09-08 EP disclosed