SCHEMBL4444152

SCHEMBL4444152

C=CCCc1cccc(-c2ccc(C=C)cc2)c1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.40
ALDH1A1 P00352 2/20 0.37
GPR52 Q9Y2T5 2/20 0.36
GPR84 Q9NQS5 1/20 0.35
AGXT P21549 3/20 0.35
MMP3 P08254 1/20 0.35
PRKCI P41743 1/20 0.34
BCL2 P10415 1/20 0.34
ACMSD Q8TDX5 1/20 0.34
CTSL P07711 1/20 0.34
TSHR P16473 1/20 0.33
HDAC2 Q92769 1/20 0.33
OPRM1 P35372 1/20 0.33
OPRD1 P41143 1/20 0.33
OPRK1 P41145 1/20 0.33
GGPS1 O95749 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17027802 0.86 AGXT (0.47) PTGS2GPR52GPR84AGXTPRKCI
SCHEMBL5034608 0.83 BCL2 (0.41) PTGS2ALDH1A1GPR84AGXTMMP3
SCHEMBL4450110 0.82 ALDH1A1 (0.46) ALDH1A1GPR52TSHR
SCHEMBL27522397 0.82 PTGS2 (0.39) PTGS2GPR52GPR84AGXTMMP3
SCHEMBL3674435 0.80 TP53 (0.45) PTGS2ALDH1A1TSHROPRM1OPRD1
SCHEMBL4508221 0.79 BCL2 (0.54) PTGS2ALDH1A1AGXTMMP3PRKCI
SCHEMBL594542 0.78 ALDH1A1 (0.55) PTGS2ALDH1A1TSHRHDAC2
SCHEMBL346414 0.76 ALDH1A1 (0.52) ALDH1A1TSHR
SCHEMBL20025112 0.75 PRMT6 (0.41) PTGS2ALDH1A1AGXTMMP3CTSL
Styrene SCHEMBL8948456 0.74 ALDH1A1 (0.58) ALDH1A1GPR52TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5418276-A Styrene copolymer, syndiotactic, heat resistance, chemical resistance IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US claimed
US-5362814-A Styrene polymers with olefin monomers and diolefin monomers for impact strength in molding materials IDEMITSU KOSAN CO., LTD. (JP) 1994-11-08 US claimed
EP-1408080-B1 POLYOLEFIN RESIN COMPOSITION IDEMITSU KOSAN CO (JP) 2012-12-26 EP disclosed
US-7531605-B2 Process for producing polyolefin resin composition and polypropylene composition IDEMITSU KOSAN CO., LTD. (JP) 2009-05-12 US disclosed
EP-1375538-B1 PROCESS FOR PRODUCING POLYOLEFIN RESIN COMPOSITION AND POLYPROPYLENE COMPOSITION IDEMITSU KOSAN CO (JP) 2008-01-09 EP disclosed
US-7193013-B2 Polyolefin resin composition IDEMITSU KOSAN CO. LTD. (JP) 2007-03-20 US disclosed
US-7189788-B2 Polyolefin resin composition IDEMITSU KOSAN CO. LTD. (JP) 2007-03-13 US disclosed
EP-1367093-B1 POLYOLEFIN RESIN COMPOSITION IDEMITSU KOSAN CO (JP) 2005-12-14 EP disclosed
US-20040176520-A1 Polyolefin resin composition IDEMITSU KOSAN CO. LTD. (JP) 2004-09-09 US disclosed
US-20040106738-A1 Process for producing polyolefin resin composition and polypropylene composition IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-06-03 US disclosed
US-20040072950-A1 High strength, chemical resistance, weatherproofing molding materials; graft polymers IDEMITSU KOSAN CO. LTD. (JP) 2004-04-15 US disclosed
EP-0667359-B1 OLEFIN COPOLYMERS AND PROCESS FOR PRODUCING THE SAME IDEMITSU KOSAN CO (JP) 2004-03-31 EP disclosed
EP-1375538-A1 PROCESS FOR PRODUCING POLYOLEFIN RESIN COMPOSITION AND POLYPROPYLENE COMPOSITION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-01-02 EP disclosed
EP-1367093-A1 POLYOLEFIN RESIN COMPOSITION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-12-03 EP disclosed
EP-0559108-B1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN CO (JP) 1997-05-28 EP disclosed
US-5608009-A OLEFIN-DIOLEFIN GRAFT POLYMER IDEMITSU KOSAN CO., LTD. (JP) 1997-03-04 US disclosed
EP-0667359-A1 OLEFIN COPOLYMERS AND PROCESS FOR PRODUCING THE SAME IDEMITSU KOSAN COMPANY LIMITED (JP) 1995-08-16 EP disclosed
US-5418276-A Styrene copolymer, syndiotactic, heat resistance, chemical resistance IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US disclosed
US-5362814-A Styrene polymers with olefin monomers and diolefin monomers for impact strength in molding materials IDEMITSU KOSAN CO., LTD. (JP) 1994-11-08 US disclosed
EP-0559108-A1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-09-08 EP disclosed