Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | HPGD | P15428 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | RECQL | P46063 | 4/20 | 0.59 |
| ▸ | APEX1 | P27695 | 3/20 | 0.59 |
| ▸ | BLM | P54132 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA4 | P22748 | 2/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoquinone SCHEMBL4443896 | 0.97 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4ETDP1HSD17B10 | |
| Benzoquinone SCHEMBL27530006 | 0.89 | TDP1 (0.53) | ALDH1A1HPGDKDM4ETDP1HSD17B10 | |
| Benzoquinone SCHEMBL8027191 | 0.87 | TDP1 (0.55) | ALDH1A1HPGDKDM4ETDP1HSD17B10 | |
| Benzoquinone SCHEMBL11668509 | 0.87 | TDP1 (0.55) | ALDH1A1HPGDKDM4ETDP1HSD17B10 | |
| Benzoquinone SCHEMBL27471771 | 0.83 | CYP3A4 (0.55) | ALDH1A1HPGDKDM4ETDP1HSD17B10 | |
| Catechol SCHEMBL28084016 | 0.80 | — | — | |
| Pyrogallol SCHEMBL25396043 | 0.80 | ALDH1A1 (0.67) | ALDH1A1HPGDKDM4ETDP1HSD17B10 | |
| Questiomycin B SCHEMBL11060308 | 0.79 | ALOX15 (0.71) | ALDH1A1HPGDKDM4ETDP1HSD17B10 | |
| Benzoquinone SCHEMBL9052881 | 0.79 | KDM4E (0.44) | ALDH1A1HPGDKDM4ETDP1HSD17B10 | |
| Catechol SCHEMBL2241272 | 0.77 | ALDH1A1 (0.83) | ALDH1A1HPGDKDM4ETDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140378522-A1 | UNIFYING MECHANISM AND METHODS TO PREVENT CANCER AND NEURODEGENERATIVE DISEASES | PREVENTION, L.L.C. (US) | 2014-12-25 | — | — | US | disclosed |
| US-20090312391-A1 | UNIFYING MECHANISM AND METHODS TO PREVENT CANCER AND NEURODEGENERATIVE DISEASES | PREVENTION, L.L.C. (US) | 2009-12-17 | — | — | US | disclosed |
| US-20050164911-A1 | By administering N-Acetylcysteine (NAC), and/or melatonin; cancer diagnosis by detecting or determining the amount of dopamine metabolites; quinone reductase inducer, lipoic acid or salt, and/or resveratrol or salt may be co-administered | PREVENTION LLC | 2005-07-28 | — | — | US | disclosed |
| WO-2003077900-A1 | A UNIFYING MECHANISM AND METHODS TO PREVENT CANCER AND NEURODEGENERATIVE DISEASES | PREVENTION, L.L.C. (US) | 2003-09-25 | — | — | WO | disclosed |