⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30511 | 1.00 | — | — | |
| SCHEMBL9279532 | 1.00 | — | — | |
| SCHEMBL1254524 | 1.00 | — | — | |
| SCHEMBL4452609 | 1.00 | — | — | |
| SCHEMBL245244 | 1.00 | — | — | |
| SCHEMBL17681496 | 1.00 | — | — | |
| SCHEMBL9047529 | 1.00 | — | — | |
| SCHEMBL24870211 | 0.97 | MBTD1 (0.39) | — | |
| SCHEMBL2378409 | 0.97 | MBTD1 (0.39) | — | |
| Lithium SCHEMBL29834968 | 0.97 | MBTD1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116615227-A | Minimum length shuttle peptide suitable for transduction of Cas9-RNP and other nucleoprotein loads and variants thereof | 费尔丹生物公司 | 2023-08-18 | — | — | CN | claimed |
| US-20090023661-A1 | Use of Antagonists of the Bradykinin B2 Receptor for the Treatment of Osteoarthrosis | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2009-01-22 | — | — | US | claimed |
| EP-1594520-A2 | USE OF BRADYKININ-B2 RECEPTOR ANTAGONISTS FOR TREATING OSTEOARTHROSIS | Sanofi-Aventis Deutschland GmbH (DE) | 2005-11-16 | — | — | EP | claimed |
| US-20040248809-A1 | Use of antagonists of the bradykinin B2 receptor for the treatment of osteoarthrosis | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-12-09 | — | — | US | claimed |
| WO-2004069266-A2 | USE OF BRADYKININ-B2 RECEPTOR ANTAGONISTS FOR TREATING OSTEOARTHROSIS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-08-19 | — | — | WO | claimed |
| EP-0370453-B1 | Peptides having a Brady kinine-inhibiting activity | HOECHST AG (DE) | 1994-06-15 | — | — | EP | claimed |
| EP-0370453-A2 | Peptides having a Brady kinine-inhibiting activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-30 | — | — | EP | claimed |
| CN-116615227-A | Minimum length shuttle peptide suitable for transduction of Cas9-RNP and other nucleoprotein loads and variants thereof | 费尔丹生物公司 | 2023-08-18 | — | — | CN | disclosed |
| US-10017441-B2 | Direct anti-markovnikov addition of acids to alkenes | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2018-07-10 | — | — | US | disclosed |
| US-9556230-B2 | TFPI inhibitors and methods of use | Baxalta GmbH (CH) | 2017-01-31 | — | — | US | disclosed |
| US-20150232514-A1 | TFPI INHIBITORS AND METHODS OF USE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-08-20 | — | — | US | disclosed |
| US-9062057-B2 | CCR5 antagonists for treating HIV | PURDUE RESEARCH FOUNDATION (US) | 2015-06-23 | — | — | US | disclosed |
| US-20140221420-A1 | CCR5 ANTAGONISTS FOR TREATING HIV | PURDUE RESEARCH FOUNDATION (US) | 2014-08-07 | — | — | US | disclosed |
| EP-0370453-B1 | Peptides having a Brady kinine-inhibiting activity | HOECHST AG (DE) | 1994-06-15 | — | — | EP | disclosed |
| EP-0370453-A2 | Peptides having a Brady kinine-inhibiting activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-30 | — | — | EP | disclosed |
| US-4691022-A | Process for the preparation of monocyclic, bicyclic and tricyclic aminoacids | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-01 | — | — | US | disclosed |
| US-4624962-A | HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-11-25 | — | — | US | disclosed |
| US-4515803-A | HYPOTENSIVES | Hoechst Aktiengesellschafat (DE) | 1985-05-07 | — | — | US | disclosed |
| EP-0132580-A1 | Process for the preparation of mono, bi and tricyclic aminoacids | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-02-13 | — | — | EP | disclosed |
| EP-0074070-A1 | Derivatives of urea, process for the preparation thereof, remedies containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-03-16 | — | — | EP | disclosed |