Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24870211 | 1.00 | MBTD1 (0.39) | MBTD1L3MBTL3ALDH1A1EPAS1MAPK1 | |
| SCHEMBL16150283 | 1.00 | MBTD1 (0.39) | MBTD1L3MBTL3ALDH1A1EPAS1MAPK1 | |
| SCHEMBL4452609 | 0.97 | — | — | |
| SCHEMBL4450273 | 0.97 | — | — | |
| SCHEMBL17681496 | 0.97 | — | — | |
| SCHEMBL245244 | 0.97 | — | — | |
| SCHEMBL9047529 | 0.97 | — | — | |
| SCHEMBL30511 | 0.97 | — | — | |
| SCHEMBL1254524 | 0.97 | — | — | |
| SCHEMBL9279532 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648333-A | POLYPEPTIDES FOR ANTIINFLAMMATORY AGENTS, WOUND HEALING AGENTS, ANTIALLERGENS OR CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-15 | — | — | US | claimed |
| EP-0488059-B1 | Use of a combination of an ace inhibitor with a calcium antagonist in the treatment of proteinuria | HOECHST AG (DE) | 1995-09-06 | — | — | EP | claimed |
| EP-0243645-B1 | Compounds having a nootropic activity, agents containing them and their use in the treatment and prophylaxis of cognitive malfunctions | HOECHST AG (DE) | 1994-03-16 | — | — | EP | claimed |
| EP-0417473-B1 | TREATMENT OF CARDIAC AND ALSO VASCULAR HYPERTROPHY AND HYPERPLASIA | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-15 | — | — | EP | claimed |
| EP-0265685-B1 | COMBINATION OF ACE INHIBITORS WITH CALCIUM ANTAGONISTS, AND THEIR USE IN MEDICINES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-29 | — | — | EP | claimed |
| EP-0488059-A2 | Use of a combination of an ace inhibitor with a calcium antagonist in the treatment of proteinuria | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-06-03 | — | — | EP | claimed |
| US-5055483-A | NOVEL AMINO ACID GLYCERIDES, LEARNING MEDICAMENTS CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | claimed |
| EP-0417473-A1 | Treatment of cardiac and also vascular hypertrophy and hyperplasia | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-20 | — | — | EP | claimed |
| EP-0344572-A2 | Composition of angiotensin-converting-enzyme inhibitor with calcium chanell modulators and uses thereof as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-12-06 | — | — | EP | claimed |
| EP-0331609-A2 | Angiotensin converting enzyme inhibitors having psychotropic effects | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-06 | — | — | EP | claimed |
| EP-0135182-B1 | PROCESS FOR THE PRODUCTION OF N-ALKYLATED DIPEPTIDES AND OF THEIR ESTERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-27 | — | — | EP | claimed |
| EP-0265685-A2 | Combination of ACE inhibitors with calcium antagonists, and their use in medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-05-04 | — | — | EP | claimed |
| EP-0243645-A2 | Compounds having a nootropic activity, agents containing them and their use in the treatment and prophylaxis of cognitive malfunctions | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-11-04 | — | — | EP | claimed |
| EP-0126986-B1 | PROCESS FOR PRODUCING N-ALKYLATED DIPEPTIDES AND THEIR ESTERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-08-05 | — | — | EP | claimed |
| EP-0219782-A2 | Use of angiotensin-converting enzyme inhibitors in the treatment of atherosclerosis, thrombosis and peripheral vascular disease | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-29 | — | — | EP | claimed |
| EP-0214570-A2 | N-alkylated tripeptides, process for their preparation, medicaments containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-18 | — | — | EP | claimed |
| EP-0115639-B1 | DISUBSTITUTED PROLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-04 | — | — | EP | claimed |
| EP-0158927-A2 | Process for the treatment of heart failure | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-10-23 | — | — | EP | claimed |
| EP-0158157-A1 | Method for the treatment of glaucoma | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-10-16 | — | — | EP | claimed |
| US-4525301-A | REACTING TRIFLUOROMETHANE SULFONIC ACID DERIVATIVES WITH AMINO ACID ESTERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-06-25 | — | — | US | claimed |