Styrene

Styrene

SCHEMBL4450343

C(=Cc1ccccc1)C1=C(c2ccccc2)CC1.C=Cc1ccccc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
TSHR P16473 1/20 0.48
FGF23 Q9GZV9 2/20 0.39
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
LMNA P02545 1/20 0.36
MAOB P27338 3/20 0.34
NFE2L2 Q16236 2/20 0.34
CYP19A1 P11511 2/20 0.34
MAOA P21397 2/20 0.34
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CHAT P28329 2/20 0.32
RELA Q04206 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
TRPA1 O75762 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5529589 0.91 FGF23 (0.44) ALDH1A1FGF23MEN1KMT2ALMNA
Styrene SCHEMBL3963599 0.90 ALDH1A1 (0.45) ALDH1A1TSHRFGF23MEN1KMT2A
Styrene SCHEMBL4360718 0.87 ALDH1A1 (0.45) ALDH1A1TSHRFGF23LMNAMAOB
Styrene SCHEMBL5902754 0.81 FGF23 (0.38) ALDH1A1TSHRFGF23MEN1KMT2A
SCHEMBL6746784 0.80 FGF23 (0.51) ALDH1A1FGF23MEN1KMT2ALMNA
(Z)-1,2-Diphenylethene SCHEMBL27498688 0.77 ALDH1A1 (0.82) ALDH1A1TSHRMEN1KMT2AMAOB
(Z)-1,2-Diphenylethene SCHEMBL28371714 0.74 ALDH1A1 (0.78) ALDH1A1TSHRMEN1KMT2AMAOB
SCHEMBL368442 0.74 ALDH1A1 (0.78) ALDH1A1TSHRMEN1KMT2AMAOB
SCHEMBL16499669 0.74 ALDH1A1 (0.78) ALDH1A1TSHRMEN1KMT2AMAOB
(Z)-1,2-Diphenylethene SCHEMBL27667013 0.74 ALDH1A1 (0.61) ALDH1A1TSHRMEN1KMT2AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1384752-B1 INSULATED ELECTRIC WIRE YAZAKI CORP (JP) 2009-10-28 EP disclosed
US-6894227-B2 Insulated electric wire YAZAKI CORPORATION (JP) 2005-05-17 US disclosed
US-20040168820-A1 INSULATED ELECTRIC WIRE YAZAKI CORPORATION (JP) 2004-09-02 US disclosed
EP-1384752-A1 INSULATED ELECTRIC WIRE YAZAKI CORPORATION (JP) 2004-01-28 EP disclosed