Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | APAF1 | O14727 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | RAD52 | P43351 | 3/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.56 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.56 |
| ▸ | FYN | P06241 | 2/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9822937 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2KMT2ACYP3A4LMNATSHR | |
| SCHEMBL26657537 | 0.79 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2ACYP3A4LMNATSHR | |
| Hydrochloric Acid SCHEMBL1934509 | 0.77 | SMN1; SMN2 (0.59) | SMN1; SMN2KMT2ACYP3A4LMNATSHR | |
| SCHEMBL4288922 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2ACYP3A4LMNATSHR | |
| SCHEMBL11057809 | 0.76 | SMN1; SMN2 (0.57) | SMN1; SMN2KMT2ACYP3A4LMNATSHR | |
| Hydrochloric Acid SCHEMBL426560 | 0.76 | KMT2A (0.60) | SMN1; SMN2KMT2ACYP3A4LMNATSHR | |
| Hydrochloric Acid SCHEMBL29999168 | 0.75 | KMT2A (0.65) | SMN1; SMN2KMT2ACYP3A4LMNATSHR | |
| SCHEMBL19074259 | 0.75 | LMNA (0.63) | SMN1; SMN2KMT2ACYP3A4LMNATSHR | |
| Hydrochloric Acid SCHEMBL2761472 | 0.74 | LMNA (0.61) | SMN1; SMN2KMT2ACYP3A4LMNATSHR | |
| SCHEMBL5936853 | 0.74 | KCNA3 (0.48) | SMN1; SMN2KMT2ACYP3A4LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060197067-A1 | Radiation-absorbing materials, ophthalmic compositions containing same, and method of treating ophthalmic devices | BAUSCH & LOMB INCORPORATED | 2006-09-07 | — | — | US | claimed |
| EP-1339418-B1 | IMPROVED OPHTHALMIC AND CONTACT LENS SOLUTIONS CONTAINING SIMPLE SACCHARIDES AS PRESERVATIVE ENHANCERS | FXS VENTURES LLC (US) | 2009-09-23 | — | — | EP | disclosed |
| WO-2006096422-A1 | RADIATION-ABSORBING MATERIALS, OPHTHALMIC COMPOSITIONS CONTAINING SAME, AND METHOD OF TREATING OPHTHALMIC DEVICES | BAUSCH & LOMB INCORPORATED (US) | 2006-09-14 | — | — | WO | disclosed |
| US-6793941-B1 | HYDROGEN PEROXIDE-FREE OPHTHALMIC SOLUTION COMPRISED OF NATURALLY- OCCURRING MICROBICIDAL COMPOUND SELECTED FROM: ALLICIN, AUCUBIN, BILBERRY EXTRACT, CAFFEIC ACID, CHLOROGENIC ACID, FERULIC ACID, NARINGIN, OLEUROPEIN, AND RUTIN | NATURAL DISINFECTANT TECHNOLOGIES, INC. (AN) | 2004-09-21 | — | — | US | disclosed |
| EP-1102602-B1 | CONTACT LENS AND OPHTHALMIC SOLUTIONS | NDT INC (US) | 2004-04-21 | — | — | EP | disclosed |
| EP-1102602-A1 | CONTACT LENS AND OPHTHALMIC SOLUTIONS | NDT, Inc. (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000007634-A1 | CONTACT LENS AND OPHTHALMIC SOLUTIONS | NDT, INC. (US) | 2000-02-17 | — | — | WO | disclosed |
| US-4485176-A | Turbidimetric method for measuring protein in urine and cerebrospinal fluid | E. I. DU PONT DE NEMOURS & COMPANY (US) | 1984-11-27 | — | — | US | disclosed |