SCHEMBL510771

SCHEMBL510771

Clc1ccc(-c2ccccc2)c(Cl)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.61
TP53 P04637 2/20 0.59
NPC1 O15118 1/20 0.59
ALDH1A1 P00352 1/20 0.59
HPGD P15428 1/20 0.59
TSHR P16473 1/20 0.59
RAB9A P51151 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
HSD17B10 Q99714 1/20 0.59
CYP2A6 P11509 1/20 0.58
CSNK2A1 P68400 2/20 0.57
HSD11B1 P28845 1/20 0.56
SRD5A2 P31213 1/20 0.55
CYP1A2 P05177 1/20 0.50
DPP4 P27487 2/20 0.49
MARS1 P56192 3/20 0.48
CYP3A4 P08684 1/20 0.46
GRM2 Q14416 1/20 0.46
MEN1 O00255 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29788257 1.00 AHR (0.61) AHRTP53NPC1ALDH1A1HPGD
Methane SCHEMBL28774809 0.96 AHR (0.57) AHRTP53NPC1ALDH1A1HPGD
Sulfur Dioxide SCHEMBL27833699 0.92 AHR (0.53) AHRTP53NPC1ALDH1A1HPGD
SCHEMBL2933108 0.85 AHR (0.67) AHRTP53NPC1ALDH1A1HPGD
SCHEMBL2235302 0.84 AHR (0.59) AHRTP53NPC1ALDH1A1HPGD
SCHEMBL5050876 0.83 CYP1A2 (0.52) TP53NPC1ALDH1A1HPGDTSHR
SCHEMBL11855959 0.82 AHR (0.53) AHRTP53NPC1ALDH1A1HPGD
SCHEMBL25501507 0.81 ALDH1A1 (0.47) AHRTP53NPC1ALDH1A1HPGD
Perchlorate SCHEMBL10496066 0.81 AHR (0.47) AHRTP53NPC1ALDH1A1HPGD
Perchlorate SCHEMBL9172137 0.81 AHR (0.47) AHRTP53NPC1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
EP-0968739-B1 Method for decomposing halogenated aliphatic and aromatic compounds CANON KK (JP) 2010-06-16 EP claimed
US-7304065-B2 Melanin concentrating hormone antagonists THE PROCTER & GAMBLE COMPANY (US) 2007-12-04 US claimed
CN-101068773-A Melanin concentrating hormone antagonists PROCTER & GAMBLE (US) 2007-11-07 CN claimed
US-20050075324-A1 Melanin concentrating hormone antagonists THE PROCTER & GAMBLE COMPANY (US) 2005-04-07 US claimed
EP-1005881-B1 Method and apparatus for decomposing halogenated aliphatic hydrocarbon compounds or aromatic compounds CANON KK (JP) 2005-01-19 EP claimed
US-6616815-B2 Contacting under irradiation with light a medium containing at least one of a halogenated aliphatic hydrocarbon compound and an aromatic compound with functional water produced by electrolysis of water containing an electrolyte CANON KABUSHIKI KAISHA (JP) 2003-09-09 US claimed
US-20030164286-A1 Apparatus for decomposing halogenated aliphatic hydrocarbon compounds or aromatic compounds CANON KABUSHIKI KAISHA (JP) 2003-09-04 US claimed
US-20020163135-A1 METHOD FOR DECOMPOSING HALOGENATED ALIPHATIC HYDROCARBON COMPOUNDS OR AROMATIC COMPOUNDS, METHOD FOR CLEANING MEDIUM CONTAMINATED WITH AT LEAST ONE OF THESE COMPOUNDS, AND APPARATUS FOR THESE CANON KABUSHIKI KAISHA (JP) 2002-11-07 US claimed
US-20020130030-A1 METHOD OF DECOMPOSING HALOGENATED ALIPHATIC HYDROCARBON COMPOUNDS OR AROMATIC COMPOUNDS AND APPARATUS TO BE USED FOR THE SAME AS WELL AS METHOD OF CLARIFYING EXHAUST GAS AND APPARATUS TO BE USED FOR THE SAME CANON KABUSHIKI KAISHA (JP) 2002-09-19 US claimed
EP-1005881-A1 Method and apparatus for decomposing halogenated aliphatic hydrocarbon compounds or aromatic compounds CANON KABUSHIKI KAISHA (JP) 2000-06-07 EP claimed
EP-0968739-A1 Method and apparatus for decomposing halogenated aliphatic and aromatic compounds CANON KABUSHIKI KAISHA (JP) 2000-01-05 EP claimed
EP-0180290-B1 OMEGA-(2',4'-DIHALOBIPHENYLYL)OXO ALKANOIC ACIDS AND PROCESS FOR THEIR PREPARATION SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) 1987-10-28 EP claimed
EP-0180290-A1 Omega-(2',4'-dihalobiphenylyl)oxo alkanoic acids and process for their preparation SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) 1986-05-07 EP claimed
US-20250303213-A1 IN SITU TREATMENT SYSTEMS FOR REMEDIATION OF POLYCHLORINATED BIPHENYL CONTAMINATED BUILDING MATERIALS UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. 2025-10-02 US disclosed
US-12350535-B2 In situ treatment systems for remediation of polychlorinated biphenyl contaminated building materials UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2025-07-08 US disclosed
US-11834414-B2 1-methyl-4-[(4-phenylphenyl)sulfonylmethyl]cyclohexyanol and 1-methyl-4-[[4-(2-pyridyl)phenyl]sulfonylmethyl]cyclohexanol compounds and their therapeutic use Modern Biosciences Limited (GB) 2023-12-05 US disclosed
US-4421888-A BLENDING POLYETHYLENE TEREPHTHALATE WITH MOLDING COMPOSITION OF POLYBUTYLENE TEREPHTHALATE CELANESE CORPORATION (US) 1983-12-20 US disclosed
US-4056444-A DISTILLATION, HEAT EXCHANGE BAYER AKTIENGESELLSCHAFT (DT) 1977-11-01 US disclosed
US-3957666-A HYDRAULIC FLUIDS, HEAT TRANSFER FLUIDS MONSANTO COMPANY (US) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030164286-A1 Apparatus for decomposing halogenated aliphatic hydrocarbon compounds or aromatic compounds AHR, ARNT, TRPA1 AHR 1/4885TP53 1403/4885NPC1 3588/4885
US-20050075324-A1 Melanin concentrating hormone antagonists MCHR1, MCHR2, MC1R AHR 663/4885TP53 4806/4885NPC1 1263/4885
US-11834414-B2 1-methyl-4-[(4-phenylphenyl)sulfonylmethyl]cyclohexyanol and 1-methyl-4-[[4-(2-pyridyl)phenyl]sulfonylmethyl]cyclohexanol compounds and their therapeutic use MALT1, BCL3, MCL1 AHR 7/4885TP53 984/4885NPC1 776/4885
US-20020130030-A1 METHOD OF DECOMPOSING HALOGENATED ALIPHATIC HYDROCARBON COMPOUNDS OR AROMATIC COMPOUNDS AND APPARATUS TO BE USED FOR THE SAME AS WELL AS METHOD OF CLARIFYING EXHAUST GAS AND APPARATUS TO BE USED FOR THE SAME AHR, ARNT, TRPA1 AHR 1/4885TP53 919/4885NPC1 3228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.