SCHEMBL4450644

SCHEMBL4450644

Clc1ccc(Cl)c(-c2cc(Cl)c(Cl)c(Cl)c2)c1

nearest known ligand 0.68

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AHR P35869 10/20 0.68
CYP1B1 Q16678 1/20 0.50
TP53 P04637 3/20 0.46
HTR2B P41595 1/20 0.44
PDE4D Q08499 1/20 0.44
ALDH1A1 P00352 4/20 0.43
PTPN11 Q06124 1/20 0.41
IDO1 P14902 1/20 0.41
TSHR P16473 2/20 0.41
CYP3A4 P08684 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
RXFP1 Q9HBX9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4459046 0.83 TP53 (0.48) AHRTP53HTR2BPDE4DALDH1A1
SCHEMBL2769862 0.82 TTR (0.54) AHRTP53HTR2BPDE4DALDH1A1
SCHEMBL2908267 0.81 AHR (1.00) AHRCYP1B1TP53ALDH1A1TSHR
SCHEMBL4445026 0.81 AHR (0.67) AHRCYP1B1TP53HTR2BPDE4D
SCHEMBL2473835 0.80 AHR (0.54) AHRTP53HTR2BPDE4DALDH1A1
SCHEMBL440944 0.79 TP53 (0.61) AHRTP53HTR2BPDE4DALDH1A1
SCHEMBL29364307 0.79 TP53 (0.61) AHRTP53HTR2BPDE4DALDH1A1
SCHEMBL4453366 0.76 TP53 (0.46) AHRTP53HTR2BPDE4DALDH1A1
SCHEMBL4454535 0.76 TP53 (0.52) AHRTP53HTR2BPDE4DALDH1A1
SCHEMBL2934398 0.76 CYP2A6 (0.58) TP53HTR2BPDE4DALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
CN-112689810-B Auxiliary monitor capable of being flattened 云创科技有限公司 2025-02-11 CN disclosed
CN-116829867-A Wireless controllable lighting device 路创技术有限责任公司 2023-09-29 CN disclosed
CN-116392146-A Implantable device 上海阶梯医疗科技有限公司 2023-07-07 CN disclosed
CN-116369927-A Method for forming implanted device 上海阶梯医疗科技有限公司 2023-07-04 CN disclosed
CN-115128875-A Array substrate, array substrate preparation method and display panel 惠科股份有限公司 2022-09-30 CN disclosed
CN-114947890-A System and method for stimulating neural tissue 美敦力施美德公司 2022-08-30 CN disclosed
CN-109310867-B External charger for implantable medical devices with alignment and centering capabilities 波士顿科学神经调制公司 2022-07-15 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed