Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPRF | P10586 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL994817 | 1.00 | PTPN1 (0.36) | PTPN1PTPRCPTPRFCDC25BMEN1 | |
| SCHEMBL19547127 | 0.81 | PTPN1 (0.37) | PTPN1PTPRCPTPRFCDC25BMEN1 | |
| SCHEMBL727947 | 0.77 | PTPN1 (0.34) | PTPN1PTPRCPTPRFCDC25BMEN1 | |
| SCHEMBL994818 | 0.77 | PTPN1 (0.37) | PTPN1PTPRCPTPRFCDC25BMEN1 | |
| SCHEMBL28887375 | 0.77 | PTPN1 (0.34) | PTPN1PTPRCPTPRFCDC25BMEN1 | |
| Biphenyl SCHEMBL28193720 | 0.75 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28814401 | 0.75 | ALDH1A1 (0.33) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16334266 | 0.72 | MEN1 (0.31) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL30564919 | 0.71 | PTPN1 (0.33) | PTPN1PTPRCPTPRFCDC25BMEN1 | |
| Hydrochloric Acid SCHEMBL21835548 | 0.71 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759463-B2 | Cross-linkable resin shaped article, cross-linked resin shaped article and laminate | ZEON CORPORATION (JP) | 2014-06-24 | — | — | US | disclosed |
| EP-2653501-A1 | CROSSLINKABLE RESIN MOLDED BODY, CROSSLINKED RESIN MOLDED BODY, AND LAMINATE | Zeon Corporation (JP) | 2013-10-23 | — | — | EP | disclosed |
| US-20130267672-A1 | CROSS-LINKABLE RESIN SHAPED ARTICLE, CROSS-LINKED RESIN SHAPED ARTICLE AND LAMINATE | ZEON CORPORATION (JP) | 2013-10-10 | — | — | US | disclosed |
| EP-2077289-A1 | POLYMERIZABLE COMPOSITION, CROSSLINKABLE RESIN, PROCESS FOR PRODUCING THE SAME, AND USE | ZEON CORPORATION (JP) | 2009-07-08 | — | — | EP | disclosed |