Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 12/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 12/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | CTSG | P08311 | 2/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.39 |
| ▸ | CMA1 | P23946 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19541875 | 0.78 | HDAC1 (0.58) | HTTHDAC3HDAC1HDAC2 | |
| SCHEMBL3693343 | 0.78 | CTRB1 (0.58) | TAS1R3TAS1R1HTTMLYCDPRSS1 | |
| SCHEMBL6437199 | 0.77 | TAS1R3 (0.54) | TAS1R3TAS1R1MLYCDPRSS1CTSG | |
| SCHEMBL23604966 | 0.76 | MAPK1 (0.55) | TAS1R3TAS1R1HTTCTSL | |
| SCHEMBL28858120 | 0.75 | HTT (0.74) | TAS1R3TAS1R1HTTMLYCDHDAC3 | |
| SCHEMBL23734319 | 0.75 | TAS1R3 (0.49) | TAS1R3TAS1R1HTTMLYCDPRSS1 | |
| SCHEMBL11805171 | 0.73 | PLA2G2C (0.44) | — | |
| SCHEMBL9322958 | 0.73 | PLA2G2C (0.44) | — | |
| SCHEMBL24193420 | 0.73 | TAS1R3 (0.58) | TAS1R3TAS1R1HTTMLYCDPRSS1 | |
| SCHEMBL21534328 | 0.73 | CA2 (0.46) | HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137503-A1 | HDAC INHIBITORS AND USES THEREOF | ENVIVO PHARMACEUTICALS, INC. (US) | 2009-11-12 | — | — | WO | disclosed |