SCHEMBL4450834

SCHEMBL4450834

Cc1c(Cl)cc(O)c(O)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 9/20 0.43
TSHR P16473 8/20 0.43
HPGD P15428 5/20 0.43
SELL P14151 1/20 0.43
SELP P16109 1/20 0.43
SELE P16581 1/20 0.43
CYP3A4 P08684 4/20 0.40
HSP90AA1 P07900 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
HIF1A Q16665 2/20 0.39
TP53 P04637 1/20 0.39
ALDH1A1 P00352 5/20 0.39
TDP1 Q9NUW8 1/20 0.39
TTR P02766 1/20 0.38
ACHE P22303 1/20 0.38
CASP1 P29466 1/20 0.38
RECQL P46063 1/20 0.38
ALOX15 P16050 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26018812 0.84 HSD17B10 (0.43) HSD17B10TSHRHPGDSELLSELP
SCHEMBL22454878 0.84 HSD17B10 (0.43) HSD17B10TSHRHPGDSELLSELP
SCHEMBL7023508 0.82 HSD17B10 (0.44) HSD17B10TSHRHPGDSELLSELP
SCHEMBL5588947 0.79 CA1 (0.43) HSD17B10TSHRHPGDCYP3A4SMN1; SMN2
SCHEMBL2659253 0.77 HSD17B10 (0.50) HSD17B10TSHRHPGDSELLSELP
SCHEMBL10820981 0.76 HSD17B10 (0.46) HSD17B10TSHRHPGDSELLSELP
SCHEMBL2220478 0.75 SELL (0.50) HSD17B10HPGDSELLSELPSELE
SCHEMBL134043 0.75 HSD17B10 (0.50) HSD17B10TSHRHPGDSELLSELP
SCHEMBL6678885 0.74 HSD17B10 (0.43) HSD17B10TSHRHPGDSELLSELP
SCHEMBL10769365 0.74 HSD17B10 (0.65) HSD17B10TSHRHPGDCYP3A4HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101219940-A Parachlorophenol hydroxyl radical resorcinol formaldehyde, production and application in sewage water detection of the same UNIV NORTHWEST NORMAL (CN) 2008-07-16 CN claimed
JP-11081150-A None JP disclosed
JP-2216281-A None JP disclosed
JP-6158548-A None JP disclosed
JP-10298873-A None JP disclosed
US-9122182-B2 Charge control agent and toner for electrostatic image development containing same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-09-01 US disclosed
US-20140038096-A1 CHARGE CONTROL AGENT AND TONER FOR ELECTROSTATIC IMAGE DEVELOPMENT CONTAINING SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-02-06 US disclosed
CN-101417961-B Anion receptor based on nitro phenylhydrazone and phenolic hydroxyl and preparation of anion test paper and use thereof UNIV NORTHWEST NORMAL 2012-07-25 CN disclosed
CN-101417989-B Anion receptor based on nitrofuran formyl hydrazone and phenolic hydroxyl and preparation and use of organagel thereof UNIV NORTHWEST NORMAL 2011-05-11 CN disclosed
US-7586009-B2 Bis-(hydroxybenzaldehyde) compound and novel polynuclear polyphenol compound derived therefrom and method for production thereof HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2009-09-08 US disclosed
CN-101417961-A Anion receptor based on nitro phenylhydrazone and phenolic hydroxyl and preparation of anion test paper and use thereof UNIV NORTHWEST NORMAL (CN) 2009-04-29 CN disclosed
CN-101417989-A Anion receptor based on nitrofuran formyl hydrazone and phenolic hydroxyl and preparation and use of organagel thereof UNIV NORTHWEST NORMAL (CN) 2009-04-29 CN disclosed
US-20090076310-A1 NOVEL BIS-(HYDROXYBENZALDEHYDE) COMPOUND AND NOVEL POLYNUCLEAR POLYPHENOL COMPOUND DERIVED THEREFROM AND METHOD FOR PRODUCTION THEREOF HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2009-03-19 US disclosed
CN-101219940-A Parachlorophenol hydroxyl radical resorcinol formaldehyde, production and application in sewage water detection of the same UNIV NORTHWEST NORMAL (CN) 2008-07-16 CN disclosed
JP-H1181150-A TREATMENT OF POLYESTER YARN FOR REINFORCING RUBBER UNITIKA LTD 1999-03-26 JP disclosed
JP-H10298873-A TREATMENT OF POLYESTER FIBER FOR REINFORCING RUBBER UNITIKA LTD 1998-11-10 JP disclosed
JP-H06158548-A TREATMENT OF POLYESTER FIBER FOR RUBBER REINFORCEMENT UNITIKA LTD 1994-06-07 JP disclosed
JP-H02216281-A METHOD FOR TREATING POLYESTER FIBER FOR REINFORCING RUBBER UNITIKA LTD 1990-08-29 JP disclosed
US-4436804-A Light-sensitive polymeric diazonium condensates and reproduction compositions and materials therewith AMERICAN HOECHST CORPORATION (US) 1984-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090076310-A1 NOVEL BIS-(HYDROXYBENZALDEHYDE) COMPOUND AND NOVEL POLYNUCLEAR POLYPHENOL COMPOUND DERIVED THEREFROM AND METHOD FOR PRODUCTION THEREOF DDT, PAH, HPD HSD17B10 681/4885TSHR 4624/4885HPGD 151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.