SCHEMBL4451129

SCHEMBL4451129

c1ccc2cc(-c3cc4ccc5cccc6ccc(c3-c3ccc7ccccc7c3)c4c56)ccc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.49
ERBB2 P04626 1/20 0.49
FYN P06241 1/20 0.49
MAOA P21397 1/20 0.49
ACHE P22303 1/20 0.49
AHR P35869 1/20 0.49
GSTP1 P09211 1/20 0.46
HDAC4 P56524 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
GPR84 Q9NQS5 1/20 0.41
ALDH1A1 P00352 4/20 0.41
HPGD P15428 4/20 0.41
HSD17B10 Q99714 4/20 0.41
TSHR P16473 3/20 0.41
TP53 P04637 1/20 0.41
MAPK1 P28482 1/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
HIF1A Q16665 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5820554 0.86 GSTP1 (0.42) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL985118 0.84 CYP1A2 (0.46) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4451069 0.83 CYP1A2 (0.52) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL2789566 0.82 GSTP1 (0.52) CYP1A2ERBB2FYNMAOAACHE
Hydrogen Sulfide SCHEMBL28320580 0.81 CYP1A2 (0.50) CYP1A2ERBB2FYNMAOAACHE
Ammonia Solution, Strong SCHEMBL27495767 0.81 CYP1A2 (0.50) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL27367886 0.80 GSTP1 (0.53) CYP1A2ERBB2FYNMAOAACHE
Ammonia Solution, Strong SCHEMBL16835567 0.80 HSD17B1 (0.48) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL5084432 0.80 CYP1A2 (0.45) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4153121 0.79 GSTP1 (0.48) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090179196-A1 Pyrene-Based Organic Compound, Transistor Material and Light-Emitting Transistor Device KYUSHU UNIVERSITY (JP) 2009-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090179196-A1 Pyrene-Based Organic Compound, Transistor Material and Light-Emitting Transistor Device PPOX, JUP, TARDBP CYP1A2 49/4885ERBB2 3775/4885FYN 2913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.