Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7536676 | 0.86 | THRB (0.44) | THRBALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL2307504 | 0.86 | THRB (0.44) | THRBALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL9274200 | 0.86 | THRB (0.44) | THRBALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL9274205 | 0.79 | THRB (0.55) | THRBALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL9274202 | 0.79 | THRB (0.55) | THRBALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL27533433 | 0.79 | THRB (0.55) | THRBALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL1615681 | 0.77 | NAAA (0.40) | THRBALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL1922495 | 0.76 | NAAA (0.37) | THRBALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL4369901 | 0.75 | HCAR2 (0.36) | — | |
| SCHEMBL1337905 | 0.75 | NPSR1 (0.42) | THRBALDH1A1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976934-A4 | RADIATION CURABLE SYSTEM | GARNETT JOHN LYNDON (AU) | 2009-05-13 | — | — | EP | disclosed |
| EP-1976934-A1 | RADIATION CURABLE SYSTEM | Garnett, John Lyndon (AU) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007079541-A1 | RADIATION CURABLE SYSTEM | GARNETT JOHN LYNDON (AU) | 2007-07-19 | — | — | WO | disclosed |