SCHEMBL4451307

SCHEMBL4451307

CCCC=c1ccc(=CCCC)cc1

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.39
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28167521 0.89 TRPA1 (0.34) TRPA1
SCHEMBL9461285 0.82 TSHR (0.39) TSHRALDH1A1
SCHEMBL28287466 0.66 TRPA1 (0.50) TRPA1TSHRALDH1A1
SCHEMBL4390684 0.65
SCHEMBL28294019 0.63
SCHEMBL12006472 0.63
SCHEMBL10977538 0.62
SCHEMBL5358981 0.62 ALDH1A1 (0.37) TRPA1TSHRALDH1A1
SCHEMBL29187652 0.62 TSHR (0.33) TRPA1TSHRALDH1A1
SCHEMBL817586 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7531588-B2 Silane compositions, processes for their preparation and rubber compositions containing same MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-05-12 US disclosed
EP-1789423-A2 SILANE COMPOSITIONS, PROCESSES FOR THEIR PREPARATION AND RUBBER COMPOSITIONS CONTAINING SAME General Electric Company (US) 2007-05-30 EP disclosed
US-20060281841-A1 Silane compositions, processes for their preparation and rubber compositions containing same MOMENTIVE PERFORMANCE MATERIALS INC. 2006-12-14 US disclosed
WO-2006015010-A2 SILANE COMPOSITIONS, PROCESSES FOR THEIR PREPARATION AND RUBBER COMPOSITIONS CONTAINING SAME GENERAL ELECTRIC COMPAMY (US) 2006-02-09 WO disclosed
US-20060025506-A1 Silane compositions, processes for their preparation and rubber compositions containing same MOMENTIVE PERFORMANCE MATERIALS INC. 2006-02-02 US disclosed