SCHEMBL5358981

SCHEMBL5358981

CCC[CH]c1ccc([CH]CCC)cc1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
ALDH3A1 P30838 3/20 0.37
ALDH1A3 P47895 3/20 0.37
KMT2A Q03164 2/20 0.33
TSHR P16473 1/20 0.33
CYP2A6 P11509 1/20 0.33
TRPA1 O75762 1/20 0.30
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1611178 0.89 CYP2A6 (0.50) KMT2ACYP2A6MEN1
SCHEMBL7222635 0.87 APP (0.41) ALDH1A1KMT2ATSHRMEN1
SCHEMBL293565 0.87 HSD17B10 (0.48) ALDH3A1ALDH1A3CYP2A6TRPA1
SCHEMBL1610150 0.87 ALDH1A1 (0.44) ALDH1A1KMT2ATSHRCYP2A6
SCHEMBL653095 0.87 NFE2L2 (0.43) KMT2ATRPA1MEN1
SCHEMBL18243003 0.87 APP (0.39) ALDH1A1ALDH3A1ALDH1A3
SCHEMBL5641505 0.87 ALDH1A1 (0.50) ALDH1A1KMT2ATSHRMEN1
SCHEMBL18378139 0.87 LMNA (0.39) ALDH1A1ALDH3A1ALDH1A3KMT2ACYP2A6
SCHEMBL135039 0.86 ALDH1A1 (0.43) ALDH1A1KMT2ATSHRCYP2A6TRPA1
SCHEMBL1610001 0.85 LPL (0.43) ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007149163-A2 BIS-QUATERNARY AMMONIUM SALTS AND METHODS FOR MODULATING NEURONAL NICOTINIC ACETYLCHOLINE RECEPTORS UNIVERSITY OF KENTUCKY (US) 2007-12-27 WO claimed
US-6906226-B2 Hydroxymethyl-substituted polyfunctional phenols HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2005-06-14 US disclosed
EP-1501830-A1 7-ARYL-3,9-DIAZABICYCLO[3.3.1]NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES Actelion Pharmaceuticals Ltd. (CH) 2005-02-02 EP disclosed
WO-2003093267-A1 7-ARYL-3,9-DIAZABICYCLO(3.3.1)NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES ACTELION PHARMACEUTICALS LTD (CH) 2003-11-13 WO disclosed