Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SULT1E1 | P49888 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.33 |
| ▸ | CDC25A | P30304 | 2/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.30 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.30 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.30 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.30 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.30 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.30 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.30 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.30 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8885745 | 0.84 | SULT1E1 (0.48) | SULT1E1GAATSHRALDH1A1MAPT | |
| SCHEMBL13446722 | 0.74 | SULT1E1 (1.00) | SULT1E1GAATSHRALDH1A1MAPT | |
| SCHEMBL4460072 | 0.71 | ALDH1A1 (0.61) | SULT1E1GAATSHRALDH1A1MAPT | |
| SCHEMBL26472020 | 0.66 | ALDH1A1 (0.55) | SULT1E1GAATSHRALDH1A1MAPT | |
| SCHEMBL2784576 | 0.66 | ALDH1A1 (0.55) | SULT1E1GAATSHRALDH1A1MAPT | |
| SCHEMBL29768747 | 0.64 | SULT1E1 (0.52) | SULT1E1ALDH1A1MAPTUSP2CYP3A4 | |
| SCHEMBL8670495 | 0.59 | ALOX5 (0.43) | SULT1E1ALDH1A1MAPTPTPN1DUSP3 | |
| Hypopurin A SCHEMBL31237274 | 0.58 | JUN (0.35) | SULT1E1GAATSHRMAPTCYP3A4 | |
| Fraxinellone SCHEMBL25272092 | 0.57 | GAA (1.00) | SULT1E1GAATSHRALDH1A1MAPT | |
| Fraxinellone SCHEMBL17503654 | 0.57 | GAA (1.00) | SULT1E1GAATSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865229-B2 | Marrubiin and composition for reducing snoring, package and method | PURANOX MEDICAL B.V. (NL) | 2014-10-21 | — | — | US | disclosed |
| US-20110305780-A1 | Marrubiin and composition for reducing snoring, package and method | PURANOX MEDICAL B.V. (NL) | 2011-12-15 | — | — | US | disclosed |
| EP-1915166-B1 | MARRUBIIN AND COMPOSITION FOR REDUCING SNORING, PACKAGE AND METHOD | PURANOX MEDICAL B V (NL) | 2009-05-20 | — | — | EP | disclosed |
| US-20080305192-A1 | Marrubiin and Composition For Reducing Snoring, Package and Method | PURANOX MEDICAL B.V. (NL) | 2008-12-11 | — | — | US | disclosed |
| CN-101257913-A | Marrubiin and composition for reducing snoring, package and method | PURANOX MEDICAL B V (NL) | 2008-09-03 | — | — | CN | disclosed |
| EP-1915166-A2 | MARRUBIIN AND COMPOSITION FOR REDUCING SNORING, PACKAGE AND METHOD | Puranox Medical B.V. (NL) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007018432-A2 | MARRUBIIN AND COMPOSITION FOR REDUCING SNORING, PACKAGE AND METHOD | PURANOX MEDICAL B.V. (NL) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080305192-A1 | Marrubiin and Composition For Reducing Snoring, Package and Method | NISCH, UTRN, MTPN | SULT1E1 2786/4885GAA 2861/4885TSHR 2388/4885 |
| US-20110305780-A1 | Marrubiin and composition for reducing snoring, package and method | NISCH, UTRN, MTPN | SULT1E1 2933/4885GAA 2939/4885TSHR 2744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.