SCHEMBL4451548

SCHEMBL4451548

CCc1c(C(=O)O)nn(-c2ccc(Cl)cc2Cl)c1-c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 6/20 0.57
CNR1 P21554 5/20 0.57
MARS1 P56192 1/20 0.52
KCNH2 Q12809 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2873006 0.94 CNR2 (0.61) CNR2CNR1
Hydrochloric Acid SCHEMBL9160043 0.93 CNR2 (0.60) CNR2CNR1
SCHEMBL2873286 0.90 CNR1 (0.70) CNR2CNR1KCNH2
Hydrochloric Acid SCHEMBL6543063 0.89 CNR1 (0.69) CNR2CNR1KCNH2
SCHEMBL9160040 0.85 CNR2 (0.61) CNR2CNR1
SCHEMBL16197758 0.84 CNR1 (0.69) CNR2CNR1
SCHEMBL909080 0.83 CNR1 (0.59) CNR2CNR1
SCHEMBL1983424 0.83 CNR2 (0.61) CNR2CNR1
SCHEMBL2865960 0.83 CNR1 (0.61) CNR2CNR1
SCHEMBL4451331 0.83 LMNA (0.61) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220264878-A1 HERBICIDAL COMPOSITION CONTAINING R-TYPE PYRIDYLOXY CARBOXYLIC ACID DERIVATIVE AND USE THEREOF QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) 2022-08-25 US disclosed
EP-4005384-A1 HERBICIDAL COMPOSITION CONTAINING R-TYPE PYRIDYLOXY CARBOXYLIC ACID DERIVATIVE AND USE THEREOF Qingdao KingAgroot Chemical Compound Co., Ltd. (CN) 2022-06-01 EP disclosed
EP-3911633-A1 HERBICIDAL SUBSTITUTED N-TETRAZOLYL ARYL CARBOXAMIDES Bayer Aktiengesellschaft (DE) 2021-11-24 EP disclosed
EP-3818830-A1 TERNARY HERBICIDAL COMPOSITION AND APPLICATION THEREOF Qingdao KingAgroot Chemical Compound Co., Ltd. (CN) 2021-05-12 EP disclosed
WO-2020148175-A1 HERBICIDAL SUBSTITUTED N-TETRAZOLYL ARYL CARBOXAMIDES BAYER AKTIENGESELLSCHAFT (DE) 2020-07-23 WO disclosed
US-7563749-B2 cyclic dioxazine substituted pyridyl sulfonylurea derivatives and a plant safener such as dymron, fenclorim, mefenpyr-diethyl, cloquintocet-mexyl etc. for the selective control of unwanted vegetation in leguminous plants BAYER CROPSCIENCE AG (DE) 2009-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220264878-A1 HERBICIDAL COMPOSITION CONTAINING R-TYPE PYRIDYLOXY CARBOXYLIC ACID DERIVATIVE AND USE THEREOF HPD, DDT, CLPP CNR2 3686/4885CNR1 3059/4885MARS1 2628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.