SCHEMBL4451559

SCHEMBL4451559

Cc1ccc(Cl)cc1.[MgH2]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6203955 0.96
SCHEMBL12679 0.96
SCHEMBL28318341 0.96 CES2 (0.62)
Fluoride SCHEMBL7653631 0.93 CES2 (0.59)
Phosphine SCHEMBL22129260 0.93
Bromide SCHEMBL28687084 0.93 CES2 (0.59)
Hydrochloric Acid SCHEMBL8996220 0.93
Hydrochloric Acid SCHEMBL28895685 0.93 CES2 (0.59)
SCHEMBL31378075 0.93
Water SCHEMBL28525892 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116554206-B Synthetic taxol resistant cell strain H460TaxRMethods of inhibiting 北京化工大学 2025-03-25 CN claimed
CN-118063354-B Synthesis method of high-purity p-toluenesulfonyl chloride 寿光诺盟化工有限公司 2024-07-16 CN claimed
CN-118063354-A Synthesis method of high-purity p-toluenesulfonyl chloride 寿光诺盟化工有限公司 2024-05-24 CN claimed
CN-117619333-A Continuous reaction system for continuously producing sartan biphenyl and continuous method for preparing sartan biphenyl 天津凯莱英医药科技发展有限公司 2024-03-01 CN claimed
CN-116554206-A Synthetic taxol resistant cell strain H460 TaxR Methods of inhibiting 北京化工大学 2023-08-08 CN claimed
US-20250214994-A1 PROCESS FOR THE PREPARATION OF PALBOCICLIB ALIVUS LIFE SCIENCES LIMITED (IN) 2025-07-03 US disclosed
CN-116554206-B Synthetic taxol resistant cell strain H460TaxRMethods of inhibiting 北京化工大学 2025-03-25 CN disclosed
CN-118063354-B Synthesis method of high-purity p-toluenesulfonyl chloride 寿光诺盟化工有限公司 2024-07-16 CN disclosed
CN-118063354-A Synthesis method of high-purity p-toluenesulfonyl chloride 寿光诺盟化工有限公司 2024-05-24 CN disclosed
CN-117619333-A Continuous reaction system for continuously producing sartan biphenyl and continuous method for preparing sartan biphenyl 天津凯莱英医药科技发展有限公司 2024-03-01 CN disclosed
CN-113527079-B Method for preparing 2-isopropenyl-5-methyl-4-hexenoic acid and derivative alcohol and carboxylic ester thereof 信越化学工业株式会社 2023-11-14 CN disclosed
CN-116554206-A Synthetic taxol resistant cell strain H460 TaxR Methods of inhibiting 北京化工大学 2023-08-08 CN disclosed
CN-104072387-B Preparation method of 2-cyano-4' -methyl biphenyl CHANGYI HANXING MEDICAL SCIENCE Co.,Ltd. (CN) 2016-01-06 CN disclosed
CN-104072387-A Preparation method of 2-cyano-4' -methyl biphenyl CHANGYI HANXING MEDICAL SCIENCE CO LTD 2014-10-01 CN disclosed
EP-0895992-B1 Copper complexes of optically active bisoxazolines as enantioselective catalysts in cyclopropanation reactions SUMITOMO CHEMICAL CO (JP) 2009-06-10 EP disclosed
US-6410741-B1 INSECTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-25 US disclosed
US-6072081-A Optically active bisoxazoline compounds, production and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-06-06 US disclosed
EP-0895992-A2 Copper complexes of optically active bisoxazolines as enantioselective catalysts in cyclopropanation reactions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-10 EP disclosed
US-4246176-A Synthesis of 5-aroyl-1-hydrocarbylpyrrole-2-acetic acid ETHYL CORPORATION (US) 1981-01-20 US disclosed
US-4144397-A Preparation of 2-aryl-propionic acids by direct coupling utilizing a mixed magnesium halide complex SYNTEX CORPORATION (US) 1979-03-13 US disclosed