⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12679 | 1.00 | — | — | |
| Fluoride SCHEMBL7653631 | 0.96 | CES2 (0.59) | — | |
| Phosphine SCHEMBL22129260 | 0.96 | — | — | |
| Water SCHEMBL28525892 | 0.96 | — | — | |
| Bromide SCHEMBL28687084 | 0.96 | CES2 (0.59) | — | |
| SCHEMBL31378075 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL8996220 | 0.96 | — | — | |
| SCHEMBL4451559 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL28895685 | 0.96 | CES2 (0.59) | — | |
| Water SCHEMBL9771893 | 0.96 | CES2 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10017463-B2 | Inhibitors of deubiquitinating proteases | BRANDEIS UNIVERSITY (US) | 2018-07-10 | — | — | US | disclosed |
| US-20170204055-A1 | INHIBITORS OF DEUBIQUITINATING PROTEASES | BRANDEIS UNIVERSITY (US) | 2017-07-20 | — | — | US | disclosed |
| WO-2016014522-A1 | INHIBITORS OF DEUBIQUITINATING PROTEASES | BRANDEIS UNIVERSITY (US) | 2016-01-28 | — | — | WO | disclosed |
| EP-1506175-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097609-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDFG RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-11-27 | — | — | WO | disclosed |
| EP-0280927-A1 | Mono- and diepoxide derivatives of delta 22-LL-F28249 compounds | AMERICAN CYANAMID COMPANY (US) | 1988-09-07 | — | — | EP | disclosed |