Fluoride

Fluoride

SCHEMBL7653631

Cc1ccc(Cl)cc1.F.F.F

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.59
CES1 P23141 1/20 0.59
ACHE P22303 2/20 0.57
LMNA P02545 1/20 0.57
CYP2A6 P11509 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
PTGS2 P35354 2/20 0.45
NR1H4 Q96RI1 1/20 0.45
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
DRD2 P14416 1/20 0.43
DRD4 P21917 1/20 0.43
DRD3 P35462 1/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL27260103 1.00
SCHEMBL28318341 0.96 CES2 (0.62) CES2CES1ACHELMNACYP2A6
SCHEMBL6203955 0.96
SCHEMBL12679 0.96
Hydrochloric Acid SCHEMBL28895685 0.93 CES2 (0.59) CES2CES1ACHELMNACYP2A6
Hydrochloric Acid SCHEMBL8996220 0.93
Water SCHEMBL28525892 0.93
Phosphine SCHEMBL22129260 0.93
Bromide SCHEMBL28687084 0.93 CES2 (0.59) CES2CES1ACHELMNACYP2A6
SCHEMBL4451559 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3119846-B1 AIR-WATER BARRIER SILICONE COATINGS CSL SILICONES INC (CA) 2019-08-14 EP disclosed
US-20190048227-A1 AIR-WATER BARRIER SILICONE COATINGS CSL SILICONES INC. (CA) 2019-02-14 US disclosed
US-10138394-B2 Air-water barrier silicone coatings CSL SILICONES INC. (CA) 2018-11-27 US disclosed
EP-3119846-A1 AIR-WATER BARRIER SILICONE COATINGS CSL Silicones Inc. (CA) 2017-01-25 EP disclosed
US-20170009098-A1 AIR-WATER BARRIER SILICONE COATINGS CSL SILICONES INC. (CA) 2017-01-12 US disclosed
WO-2015139135-A1 AIR-WATER BARRIER SILICONE COATINGS CSL SILICONES INC. (CA) 2015-09-24 WO disclosed
WO-2013134018-A1 COMPOSITIONS OF RESIN-LINEAR ORGANOSILOXANE BLOCK COPOLYMERS DOW CORNING CORPORATION (US) 2013-09-12 WO disclosed
US-6462117-B1 ORGANIC SOLVENT WITH NEGLIGIBLE PHOTOCHEMICAL REACTIVITY AS MEASURED BY AN OXIDATION RATE CONSTANT OF LESS THAN 1 X 1010 CM3/G MIDDLE-DOT SEC; EVAPORATION RATE OF NOT MORE THAN ABOUT 5 TIMES THAT OF N-BUTYL ACETATE, I.E., TERT-BUTYL ACETATE ARCO CHEMICAL TECHNOLOGY L.P. 2002-10-08 US disclosed
US-20020115781-A1 Coatings and inks based on solvents having negligible photochemical reactivity ARCO CHEMICAL TECHNOLOGY, L.P. (US) 2002-08-22 US disclosed