Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451666 | 1.00 | OPRK1 (0.44) | OPRK1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL4455213 | 0.82 | HCRTR1 (0.45) | SMN1; SMN2HCRTR1HCRTR2 | |
| SCHEMBL4455211 | 0.82 | HCRTR1 (0.45) | SMN1; SMN2HCRTR1HCRTR2 | |
| SCHEMBL21047795 | 0.79 | ELANE (0.53) | OPRK1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL3952272 | 0.75 | OPRK1 (0.59) | OPRK1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL16666111 | 0.72 | ELANE (0.62) | OPRK1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL4454834 | 0.71 | GAA (0.48) | NPC1RAB9AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL4454829 | 0.71 | GAA (0.48) | NPC1RAB9AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL5065261 | 0.71 | ELANE (0.65) | OPRK1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1163272 | 0.70 | NPC1 (0.61) | NPC1RAB9AALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |