Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 5/20 | 0.52 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16666111 | 0.98 | ELANE (0.62) | ELANEHDAC6OPRK1PCSK9FAAH | |
| SCHEMBL3952272 | 0.92 | OPRK1 (0.59) | ELANEOPRK1PCSK9SSTR5NPC1 | |
| SCHEMBL7698249 | 0.84 | OPRK1 (0.53) | ELANEHDAC6OPRK1PCSK9SSTR5 | |
| SCHEMBL3577272 | 0.84 | OPRK1 (0.53) | ELANEOPRK1PCSK9SSTR5NPC1 | |
| Bromide SCHEMBL3570691 | 0.83 | OPRK1 (0.52) | ELANEOPRK1PCSK9SSTR5NPC1 | |
| SCHEMBL21047795 | 0.83 | ELANE (0.53) | ELANEHDAC6OPRK1PCSK9SSTR5 | |
| SCHEMBL3477307 | 0.82 | FAAH (0.66) | ELANEHDAC6FAAHPIK3CAGAA | |
| SCHEMBL12966291 | 0.81 | OPRK1 (0.53) | ELANEOPRK1PCSK9SSTR5NPC1 | |
| SCHEMBL13564111 | 0.81 | OPRK1 (0.53) | ELANEOPRK1PCSK9SSTR5NPC1 | |
| SCHEMBL13564156 | 0.81 | OPRK1 (0.50) | ELANEHDAC6OPRK1PCSK9SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178666-B2 | 2-aminobenzoxazole process | ALBANY MOLECULAR RESEARCH, INC. (US) | 2012-05-15 | — | — | US | disclosed |