Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 5/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.40 |
| ▸ | GABRE | P78334 | 2/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455211 | 1.00 | HCRTR1 (0.45) | HCRTR1HCRTR2MPOPTGDR2POLB | |
| SCHEMBL4451670 | 0.82 | OPRK1 (0.44) | HCRTR1HCRTR2SMN1; SMN2 | |
| SCHEMBL4451666 | 0.82 | OPRK1 (0.44) | HCRTR1HCRTR2SMN1; SMN2 | |
| SCHEMBL16666112 | 0.75 | HDAC6 (0.60) | HCRTR1HCRTR2MPOPTGDR2GABRP | |
| SCHEMBL2138540 | 0.74 | FBP1 (0.46) | HCRTR1HCRTR2MPOPTGDR2GABRP | |
| SCHEMBL12966306 | 0.71 | PTGDR2 (0.52) | HCRTR1HCRTR2PTGDR2HDAC6CTSL | |
| SCHEMBL13563404 | 0.69 | PTGDR2 (0.46) | HCRTR1HCRTR2PTGDR2HDAC6CTSL | |
| SCHEMBL12966060 | 0.69 | PTGDR2 (0.48) | HCRTR1HCRTR2MPOPTGDR2HDAC6 | |
| SCHEMBL21066392 | 0.69 | HCRTR1 (0.42) | HCRTR1HCRTR2MPOPTGDR2GABRP | |
| SCHEMBL13522392 | 0.67 | HCRTR1 (0.46) | HCRTR1HCRTR2MPOPTGDR2GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |