Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.55 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.55 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.55 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.55 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26217998 | 0.90 | MEN1 (0.46) | MEN1KMT2AGRIN1GRIN2AGRIN2D | |
| SCHEMBL26218000 | 0.87 | GRIN1 (0.50) | MEN1KMT2AGRIN1GRIN2AGRIN2D | |
| SCHEMBL1786642 | 0.83 | MEN1 (0.53) | MEN1KMT2AGRIN1GRIN2AGRIN2D | |
| SCHEMBL12858118 | 0.82 | MEN1 (0.49) | MEN1KMT2AGRIN1GRIN2AGRIN2D | |
| SCHEMBL4151999 | 0.81 | MEN1 (0.52) | MEN1KMT2AGRIN1GRIN2AGRIN2D | |
| SCHEMBL5104994 | 0.81 | MEN1 (0.51) | MEN1KMT2AGRIN1GRIN2AGRIN2D | |
| Hydrochloric Acid SCHEMBL7110650 | 0.80 | MEN1 (0.59) | MEN1KMT2AGRIN1GRIN2AGRIN2D | |
| SCHEMBL5145929 | 0.80 | PKM (0.50) | MEN1KMT2AGRIN1GRIN2AGRIN2D | |
| SCHEMBL25879662 | 0.80 | — | — | |
| SCHEMBL21747117 | 0.79 | MEN1 (0.49) | MEN1KMT2AGRIN1GRIN2AGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009057140-A2 | IMPROVED PROCESS FOR MEMANTINE HYDROCHLORIDE | MSN LABORATORIES LIMITED (IN) | 2009-05-07 | — | — | WO | claimed |
| US-20230130425-A1 | AMINOADAMANTYL NITRATE COMPOUNDS AND THEIR USE TO TREAT CNS DISORDERS | PANORAMA RESEARCH, INC. | 2023-04-27 | — | — | US | disclosed |
| US-20230130425-A1 | AMINOADAMANTYL NITRATE COMPOUNDS AND THEIR USE TO TREAT CNS DISORDERS | PANORAMA RESEARCH, INC. | 2023-04-27 | — | — | US | disclosed |
| US-20200377444-A1 | AMINOADAMANTYL NITRATE COMPOUNDS AND THEIR USE TO TREAT CNS DISORDERS | PANORAMA RESEARCH, INC. | 2020-12-03 | — | — | US | disclosed |
| CN-101389594-B | Process for the preparation of adamantanamines | HEXAL AG | 2013-06-12 | — | — | CN | disclosed |
| CN-101389594-A | Process for the preparation of adamantanamines | HEXAL AG (DE) | 2009-03-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200377444-A1 | AMINOADAMANTYL NITRATE COMPOUNDS AND THEIR USE TO TREAT CNS DISORDERS | NLN, SLC1A2, AANAT | MEN1 1333/4885KMT2A 1928/4885GRIN1 98/4885 |
| US-20230130425-A1 | AMINOADAMANTYL NITRATE COMPOUNDS AND THEIR USE TO TREAT CNS DISORDERS | NLN, SLC1A2, AANAT | MEN1 1333/4885KMT2A 1928/4885GRIN1 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.