SCHEMBL4451820

SCHEMBL4451820

Clc1cc(Cl)cc(-c2cc(Cl)cc(Cl)c2Cl)c1

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.55
AHR P35869 9/20 0.50
TSHR P16473 3/20 0.44
HSD17B10 Q99714 2/20 0.44
HPGD P15428 1/20 0.44
SCN2A Q99250 1/20 0.40
CYP3A4 P08684 2/20 0.38
RECQL P46063 1/20 0.38
CES1 P23141 1/20 0.34
DNMT1 P26358 1/20 0.34
CNR2 P34972 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4453256 0.90 AHR (0.64) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL2930780 0.83 ALDH1A1 (0.69) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL4451855 0.82 AHR (0.64) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL30621950 0.82 AHR (0.64) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL4448755 0.80 AHR (0.68) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL4452357 0.80 AHR (0.45) ALDH1A1AHRTSHR
SCHEMBL2140618 0.78 CYP2A6 (0.50) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL4459668 0.78 ALDH1A1 (0.61) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL4459047 0.77 AHR (0.67) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL4451811 0.76 ALDH1A1 (0.58) ALDH1A1AHRTSHRHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119667048-A Method for quantitatively analyzing and detecting organic luminescent material of internal biphenyl fluorene 江汉大学 2025-03-21 CN claimed
CN-117126920-B Central nervous infection pathogen library building and detecting method based on nanopore sequencing platform 江苏先声医学诊断有限公司 2024-04-12 CN claimed
CN-117126920-A Central nervous infection pathogen library building and detecting method based on nanopore sequencing platform 江苏先声医学诊断有限公司 2023-11-28 CN claimed
CN-114014934-B Polychlorinated biphenyl monoclonal antibody and application thereof 江苏省农业科学院 2023-05-05 CN claimed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
US-12268734-B2 Mycoplasma vaccines and uses thereof UNIVERSITY OF SASKATCHEWAN (CA) 2025-04-08 US disclosed
CN-119667048-A Method for quantitatively analyzing and detecting organic luminescent material of internal biphenyl fluorene 江汉大学 2025-03-21 CN disclosed
CN-119455459-A Purifying and separating method for dioxin substances 浙江九安检测科技有限公司 2025-02-18 CN disclosed
CN-118574304-B Printed circuit board and manufacturing method thereof 苏州元脑智能科技有限公司 2024-11-19 CN disclosed
CN-221801621-U Desk lamp with detachable lamp holder 中山市创谷众创空间商务服务有限公司 2024-10-01 CN disclosed
CN-118575188-A Generating Artificial Intelligence (AIGC) 汉熵通信有限公司 2024-08-30 CN disclosed
CN-118574304-A Printed circuit board and manufacturing method thereof 苏州元脑智能科技有限公司 2024-08-30 CN disclosed
CN-110146695-B Method for screening human transthyretin interferent by adopting k nearest neighbor algorithm 南京理工大学 2021-12-10 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
CN-110146695-A Using the method for k nearest neighbor algorithm screening human thyroid element transporter chaff interferent 南京理工大学 2019-08-20 CN disclosed
US-8168663-B2 Pharmaceutically acceptable salt of 6-carboxy-2-(3,5 dichlorophenyl)-benzoxazole, and a pharmaceutical composition comprising the salt thereof THE SCRIPPS RESEARCH INSTITUTE (US) 2012-05-01 US disclosed
US-20100120919-A1 METHODS FOR TREATING TRANSTHYRETIN AMYLOID DISEASES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-05-13 US disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100120919-A1 METHODS FOR TREATING TRANSTHYRETIN AMYLOID DISEASES TTR, TTPA, PRNP ALDH1A1 2744/4885AHR 4301/4885TSHR 1892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.