Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.51 |
| ▸ | PPARG | P37231 | 11/20 | 0.45 |
| ▸ | PPARD | Q03181 | 8/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5365685 | 0.88 | PPARA (0.55) | PPARAPPARGPPARDABCB11CYP1A2 | |
| SCHEMBL5361328 | 0.87 | PPARA (0.48) | PPARAPPARGPPARDABCB11CYP1A2 | |
| SCHEMBL4460251 | 0.87 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL4460245 | 0.87 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL9493601 | 0.84 | MMP8 (0.49) | PPARAPPARGPPARDACACBEPHX2 | |
| SCHEMBL5360570 | 0.82 | LMNA (0.46) | PPARAPPARGPPARDEPHX2 | |
| SCHEMBL5360572 | 0.82 | LMNA (0.46) | PPARAPPARGPPARDEPHX2 | |
| SCHEMBL5360578 | 0.82 | LMNA (0.46) | PPARAPPARGPPARDEPHX2 | |
| SCHEMBL2554435 | 0.82 | PPARA (0.52) | PPARAPPARGPPARD | |
| SCHEMBL7023381 | 0.81 | PPARA (0.76) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090029429-A1 | Process for Producing Optically Active 2-Substituent-Oxy-3-(4-Substituent-Oxyphenyl) Propionic Acid Derivative | KANEKA CORPORATION (JP) | 2009-01-29 | — | — | US | disclosed |