SCHEMBL10447240

SCHEMBL10447240

C/C=C\c1cccc(C(C)CN)c1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.50
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
CNR2 P34972 1/20 0.34
AKT1 P31749 1/20 0.33
HPGD P15428 1/20 0.33
ATM Q13315 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HTR2A P28223 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11518269 0.84 HDAC4 (0.51) HDAC4HDAC2HDAC8CNR2HPGD
SCHEMBL14051358 0.80 TYR (0.46) HDAC4HDAC2HDAC8CNR2HPGD
SCHEMBL3005201 0.79 TAAR1 (0.70) TAAR1HDAC4HDAC2HDAC8HTR2A
SCHEMBL4451929 0.79 HDAC4 (0.33) HDAC4HDAC2HDAC8CNR2HPGD
SCHEMBL4451930 0.79 HDAC4 (0.33) HDAC4HDAC2HDAC8CNR2HPGD
SCHEMBL10454077 0.78 TAAR1 (0.52) TAAR1CNR2SMN1; SMN2HTR2A
SCHEMBL20931111 0.77 CNR2 (0.37) HDAC4HDAC2HDAC8CNR2HPGD
SCHEMBL15576945 0.76 PNMT (0.36) CNR2
SCHEMBL5598219 0.75 KDM4E (0.46) SMN1; SMN2
SCHEMBL29865451 0.75 KDM4E (0.46) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0371154-A1 Prepreg of reinforced imide oligomer UBE INDUSTRIES, LTD. (JP) 1990-06-06 EP disclosed
EP-0304913-A2 Terminal-modified imide oligomer and solution composition of the same UBE INDUSTRIES, LTD. (JP) 1989-03-01 EP disclosed