Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 3/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4155485 | 0.86 | FDFT1 (0.46) | FDFT1FAAHTERTALDH1A1TDP1 | |
| SCHEMBL6357892 | 0.82 | TDP1 (0.56) | FDFT1ALDH1A1TDP1 | |
| SCHEMBL9220288 | 0.79 | PNMT (0.55) | FDFT1FAAHTERTALDH1A1TAAR1 | |
| SCHEMBL16316340 | 0.79 | ALDH1A1 (0.48) | FDFT1FAAHTERTALDH1A1TDP1 | |
| SCHEMBL29857418 | 0.78 | FFAR1 (0.59) | FDFT1FAAHTDP1 | |
| SCHEMBL30543010 | 0.78 | TERT (0.53) | FDFT1TERTALDH1A1TDP1LMNA | |
| SCHEMBL10879362 | 0.77 | SLC6A4 (0.46) | FAAHALDH1A1PPARGPPARALMNA | |
| SCHEMBL13235746 | 0.77 | FDFT1 (0.48) | FDFT1FAAHALDH1A1TDP1PPARG | |
| SCHEMBL5304024 | 0.77 | FDFT1 (0.50) | FDFT1ALDH1A1TDP1MAPT | |
| SCHEMBL13719005 | 0.75 | TAAR1 (0.46) | FDFT1FAAHTERTALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009059239-A2 | REDUCING Aβ42 LEVELS AND Aβ AGGREGATION | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2009-05-07 | — | — | WO | disclosed |