SCHEMBL4452181

SCHEMBL4452181

OP(O)OCCCC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 15/20 0.50
KCNH2 Q12809 2/20 0.42
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
CHRM4 P08173 4/20 0.34
CHRM5 P08912 4/20 0.34
CHRM3 P20309 4/20 0.34
CHRM2 P08172 3/20 0.34
CHRM1 P11229 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8834475 0.93 KIF11 (0.47) KIF11KCNH2CYP3A4CYP2D6CYP2C9
SCHEMBL16822396 0.93 KIF11 (0.47) KIF11KCNH2CYP3A4CYP2D6CYP2C9
SCHEMBL4459727 0.89 KIF11 (0.44) KIF11KCNH2CYP2D6CHRM4CHRM5
SCHEMBL11865222 0.80 LMNA (0.36) KIF11KCNH2CHRM4CHRM5CHRM3
SCHEMBL705749 0.79 KIF11 (0.55) KIF11KCNH2CYP3A4CYP2D6CYP2C9
SCHEMBL28491862 0.78 KIF11 (0.59) KIF11KCNH2CYP3A4CYP2D6CYP2C9
SCHEMBL4454998 0.76 KIF11 (0.38) KIF11KCNH2CYP2C9CYP2C19
SCHEMBL2325018 0.75 KIF11 (0.55) KIF11KCNH2CYP3A4CYP2D6CYP2C9
SCHEMBL9161063 0.75 KIF11 (0.55) KIF11KCNH2CYP3A4CYP2D6CYP2C9
SCHEMBL8652182 0.74 KIF11 (0.50) KIF11KCNH2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed