SCHEMBL705749

SCHEMBL705749

[SiH3]OCCCC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 16/20 0.55
KCNH2 Q12809 2/20 0.46
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
SIGMAR1 Q99720 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL703111 0.87 KIF11 (0.48) KIF11KCNH2CYP3A4CYP2D6CYP2C9
SCHEMBL28491862 0.83 KIF11 (0.59) KIF11KCNH2CYP3A4CYP2D6CYP2C9
SCHEMBL3868241 0.80 KIF11 (0.51) KIF11KCNH2CYP3A4CYP2D6CYP2C9
SCHEMBL9161063 0.79 KIF11 (0.55) KIF11KCNH2CYP3A4CYP2D6CYP2C9
SCHEMBL8516933 0.79 KIF11 (0.55) KIF11KCNH2CYP3A4CYP2D6CYP2C9
SCHEMBL2325018 0.79 KIF11 (0.55) KIF11KCNH2CYP3A4CYP2D6CYP2C9
SCHEMBL31415572 0.79 KIF11 (0.55) KIF11KCNH2CYP3A4CYP2D6CYP2C9
SCHEMBL4452181 0.79 KIF11 (0.50) KIF11KCNH2CYP3A4CYP2D6CYP2C9
SCHEMBL9161414 0.78 KIF11 (0.64) KIF11KCNH2CYP3A4CYP2D6CYP2C9
SCHEMBL2326446 0.78 KIF11 (0.53) KIF11KCNH2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115155113-B Structure for organic silicon defoamer and synthesis method thereof 佛山市南海大田化学有限公司 2023-09-29 CN claimed
CN-115105868-B Organic silicon defoamer and preparation method thereof 佛山市南海大田化学有限公司 2023-07-18 CN claimed
CN-115105868-A Organic silicon defoaming agent and preparation method thereof 佛山市南海大田化学有限公司 2022-09-27 CN claimed
US-7129311-B2 Additives to prevent degradation of alkyl-hydrogen siloxanes ARCH SPECIALTY CHEMICALS, INC. (US) 2006-10-31 US claimed
US-20060159861-A1 Additives to prevent degradation of alkyl-hydrogen siloxanes ARCH SPECIALTY CHEMICALS, INC. (US) 2006-07-20 US claimed
EP-1573086-A2 ADDITIVES TO PREVENT DEGRADATION OF ALKYL-HYDROGEN SILOXANES Arch Specialty Chemicals, Inc. (US) 2005-09-14 EP claimed
US-20040127070-A1 Additives to prevent degradation of alkyl-hydrogen siloxanes ARCH SPECIALTY CHEMICALS, INC. 2004-07-01 US claimed
WO-2004027110-A2 ADDITIVES TO PREVENT DEGRADATION OF ALKYL-HYDROGEN SILOXANES ARCH SPECIALTY CHEMICALS, INC. (US) 2004-04-01 WO claimed
CN-115155113-B Structure for organic silicon defoamer and synthesis method thereof 佛山市南海大田化学有限公司 2023-09-29 CN disclosed
CN-115105868-B Organic silicon defoamer and preparation method thereof 佛山市南海大田化学有限公司 2023-07-18 CN disclosed
CN-115105868-A Organic silicon defoaming agent and preparation method thereof 佛山市南海大田化学有限公司 2022-09-27 CN disclosed
CN-111448224-A Urea-bonded tetrafunctional (meth) acrylate compound and composition containing same 捷恩智株式会社 2020-07-24 CN disclosed
WO-2019194108-A1 UREA-BINDING TETRAFUNCTIONAL (METH)ACRYLATE COMPOUND AND COMPOSITION CONTAINING SAME JNC株式会社 2019-10-10 WO disclosed
WO-2019194107-A1 RESIN COMPOSITION JNC株式会社 2019-10-10 WO disclosed
EP-0682086-A2 Resin composition and a method of curing the same KANSAI PAINT CO., LTD. (JP) 1995-11-15 EP disclosed
EP-0681003-A2 Resin composition and a method of curing the same KANSAI PAINT CO., LTD. (JP) 1995-11-08 EP disclosed
US-5389727-A Low temperature curing, weatherproofing KANSAI PAINT COMPANY, LIMITED (JP) 1995-02-14 US disclosed
US-5284919-A Low temperature curing, waterproofing, acid resistance KANSAI PAINT COMPANY, LIMITED (JP) 1994-02-08 US disclosed
US-5026793-A Containing hydroxy, epoxy, and silane compounds with chelate compound containing aluminum, titanium, or zironium KANSAI PAINT COMPANY LIMITED (JP) 1991-06-25 US disclosed
EP-0358238-A2 Resin compositions and a method of curing the same KANSAI PAINT CO., LTD. (JP) 1990-03-14 EP disclosed