SCHEMBL4452488

SCHEMBL4452488

COC(C=C=O)=CC1C(C)(C)C1(Cc1coc(Cc2ccccc2)c1)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4338524 0.84 IDH1 (0.36) IDH1
SCHEMBL8321135 0.83 IDH1 (0.40) IDH1
SCHEMBL7916536 0.83 IDH1 (0.40) IDH1
SCHEMBL11436250 0.83 IDH1 (0.40) IDH1
SCHEMBL7536857 0.83 IDH1 (0.40) IDH1
SCHEMBL3513116 0.83 IDH1 (0.40) IDH1
SCHEMBL739613 0.82 IDH1 (0.39) IDH1
SCHEMBL8464735 0.76 TDP1 (0.46) IDH1
SCHEMBL4598786 0.72 APP (0.35) IDH1
SCHEMBL3704273 0.72 IDH1 (0.35) IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2084214-A1 TREATED EXPANDED POLYSTYRENE FOAM Lanxess Corporation (US) 2009-08-05 EP disclosed
US-20090076090-A1 Treated Expanded Polystyrene Foam LANXESS CORPORATION (US) 2009-03-19 US disclosed
WO-2008051392-A1 TREATED EXPANDED POLYSTYRENE FOAM LANXESS CORPORATION (US) 2008-05-02 WO disclosed
US-20080096991-A1 Treated expanded polystyrene foam ATLAS ROOFING CORPORATION 2008-04-24 US disclosed
US-20050234070-A1 Agents for preserving technical materials against insects TSUBOI SHINICHI 2005-10-20 US disclosed
US-6936624-B2 Agents for preserving technical materials against insects NIHON BAYER AGROCHEM K.K. (JP) 2005-08-30 US disclosed
US-20010051643-A1 Agents for preserving technical materials against insects TSUBOI SHINICHI (JP) 2001-12-13 US disclosed
US-6323224-B1 1-(6-CHLORO-3-PYRIDYLMETHYL)-2-NITROIMINO-IMIDAZOLIDINE IS APPLIED BY SOAKING SAID WOOD PRODUCT IN OR WITH SAID COMPOUND, IMPREGNATING SAID WOOD PRODUCT WITH SAID COMPOUND, BRUSHING, SPRAYING AND DIPPING NIHON BAYER AGROCHEM K.K. (JP) 2001-11-27 US disclosed
US-5661164-A APPLYING A SYNERGISTIC MIXTURE OF CYFLUTHRIN, 1-(6-CHLORO-3-PYRIDYLMETHYL)-N-NITROIMIDAZOLIDIN-2-YLIDENE-AMINE AND A CARRIER NIHON BAYER AGROCHEM K.K. (JP) 1997-08-26 US disclosed
EP-0511541-B1 Agents for preserving wood or composite-wood materials against insects BAYER AGROCHEM KK (JP) 1996-09-04 EP disclosed
US-5196442-A Chloropyridyl compounds NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1993-03-23 US disclosed
EP-0511541-A1 Agents for preserving wood or composite-wood materials against insects NIHON BAYER AGROCHEM K.K. (JP) 1992-11-04 EP disclosed
US-5087632-A Formicidal agent for combating termites NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1992-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050234070-A1 Agents for preserving technical materials against insects TREH, GPX4, GPX1 IDH1 3876/4885
US-20010051643-A1 Agents for preserving technical materials against insects GPX1, FEN1, POT1 IDH1 3460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.