Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CCR4 | P51679 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4452813 | 0.73 | HSP90AA1 (0.45) | CCR4 | |
| SCHEMBL3453670 | 0.64 | NQO2 (0.49) | KDM4ECCR4KCNH2NR4A2 | |
| SCHEMBL2639299 | 0.63 | RAC1 (0.63) | CCR4KCNH2 | |
| Hydrochloric Acid SCHEMBL17022810 | 0.62 | RAC1 (0.64) | CCR4KCNH2 | |
| SCHEMBL14065421 | 0.61 | CCR4 (0.40) | CCR4KCNH2 | |
| SCHEMBL13750296 | 0.60 | KDM4E (0.40) | KDM4E | |
| SCHEMBL10575025 | 0.56 | ALOX15 (0.35) | KDM4E | |
| SCHEMBL2565496 | 0.56 | FDPS (0.31) | KDM4EKCNH2 | |
| SCHEMBL2565897 | 0.56 | OPRM1 (0.33) | KDM4EKCNH2 | |
| SCHEMBL2873413 | 0.56 | KDM4E (0.62) | L3MBTL1KDM4ENR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | claimed |
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | disclosed |