SCHEMBL4452902

SCHEMBL4452902

Clc1cccc(-c2c(Cl)c(Cl)cc(Cl)c2Cl)c1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.45
TAAR1 Q96RJ0 1/20 0.44
IKBKE Q14164 1/20 0.43
ALDH1A1 P00352 2/20 0.42
NOTUM Q6P988 2/20 0.41
TSHR P16473 2/20 0.41
ESR2 Q92731 1/20 0.41
NPC1 O15118 1/20 0.41
TP53 P04637 1/20 0.41
NFKB1 P19838 1/20 0.41
RAB9A P51151 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
IDO1 P14902 4/20 0.40
MAOB P27338 2/20 0.40
DHFR P00374 1/20 0.40
AHR P35869 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4450643 0.87 ALOX5 (0.42) ALOX5TAAR1IKBKEALDH1A1NOTUM
SCHEMBL4450693 0.86 ALOX5 (0.48) ALOX5TAAR1IKBKEALDH1A1NOTUM
SCHEMBL4453356 0.84 ALOX5 (0.44) ALOX5TAAR1IKBKEALDH1A1NOTUM
SCHEMBL30387433 0.84 ALOX5 (0.44) ALOX5TAAR1IKBKEALDH1A1NOTUM
SCHEMBL4459641 0.81 ALOX5 (0.48) ALOX5TAAR1IKBKEALDH1A1NOTUM
SCHEMBL4458179 0.81 ALOX5 (0.48) ALOX5TAAR1IKBKEALDH1A1NOTUM
SCHEMBL4449773 0.79 AHR (0.56) ALOX5TAAR1ALDH1A1NOTUMTSHR
SCHEMBL4452357 0.78 AHR (0.45) ALOX5TAAR1ALDH1A1NOTUMTSHR
SCHEMBL2936378 0.78 MEN1 (0.45) ALDH1A1TSHRESR2SMN1; SMN2AHR
SCHEMBL4454430 0.78 AHR (0.55) ALDH1A1TSHRTP53AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
CN-112135070-B Camera module and imaging apparatus including the same 三星电子株式会社 2025-04-25 CN disclosed
CN-115135232-B Skin and hair measurement and analysis system 科创科技有限公司 2025-01-21 CN disclosed
CN-119301662-A Display device LG电子株式会社 2025-01-10 CN disclosed
WO-2024197966-A1 INPUT SIGNAL GENERATION APPARATUS AND ELECTRONIC DEVICE 童宗伟 2024-10-03 WO disclosed
CN-118519231-A Heterogeneous integrated photoelectron chip based on optical penetrating substrate channel 杭州兰特普光电子技术有限公司 2024-08-20 CN disclosed
CN-118090020-B High-reliability intelligent pressure sensor 合肥智感科技有限公司 2024-07-19 CN disclosed
CN-118090020-A High-reliability intelligent pressure sensor 合肥智感科技有限公司 2024-05-28 CN disclosed
WO-2024103718-A1 LIQUID-COOLING HEAT DISSIPATION DEVICE, HEAT DISSIPATION SYSTEM, AND ELECTRONIC DEVICE 华为技术有限公司 2024-05-23 WO disclosed
CN-118055592-A Liquid cooling heat abstractor, cooling system and electronic equipment 华为技术有限公司 2024-05-17 CN disclosed
CN-110834141-B Bond head assembly, thermal compression bonding system, and methods of assembling and operating the same 库利克和索夫工业公司 2022-04-08 CN disclosed
CN-114199399-A Temperature sensor 和谐工业有限责任公司 2022-03-18 CN disclosed
CN-109414664-B Intelligent microfluid mixing instrument and kit 精密纳米系统有限公司 2022-03-11 CN disclosed
CN-114098975-A Robotic surgical devices, systems, and related methods 虚拟切割有限公司 2022-03-01 CN disclosed
CN-215839854-U Lumbar vertebra massager with rotation function 武汉左点科技有限公司 2022-02-18 CN disclosed
CN-215839853-U Lumbar vertebra massager with adjustable massage subassembly 武汉左点科技有限公司 2022-02-18 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed