SCHEMBL4450693

SCHEMBL4450693

Clc1cccc(-c2c(Cl)c(Cl)c(Cl)c(Cl)c2Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.48
TAAR1 Q96RJ0 2/20 0.47
IKBKE Q14164 1/20 0.46
NOTUM Q6P988 2/20 0.44
TSHR P16473 2/20 0.44
ESR2 Q92731 1/20 0.44
NPC1 O15118 1/20 0.44
TP53 P04637 1/20 0.44
NFKB1 P19838 1/20 0.44
RAB9A P51151 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
IDO1 P14902 4/20 0.42
MAOB P27338 2/20 0.42
ALDH1A1 P00352 1/20 0.42
DHFR P00374 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4452902 0.86 ALOX5 (0.45) ALOX5TAAR1IKBKENOTUMTSHR
SCHEMBL4450643 0.82 ALOX5 (0.42) ALOX5TAAR1IKBKENOTUMTSHR
SCHEMBL31222672 0.81 ALOX5 (0.65) ALOX5TAAR1NOTUMTSHRESR2
SCHEMBL817554 0.81 ALOX5 (0.65) ALOX5TAAR1NOTUMTSHRESR2
SCHEMBL4458179 0.80 ALOX5 (0.48) ALOX5TAAR1IKBKENOTUMTSHR
SCHEMBL4459641 0.80 ALOX5 (0.48) ALOX5TAAR1IKBKENOTUMTSHR
SCHEMBL4453356 0.79 ALOX5 (0.44) ALOX5TAAR1IKBKENOTUMTSHR
SCHEMBL30387433 0.79 ALOX5 (0.44) ALOX5TAAR1IKBKENOTUMTSHR
SCHEMBL4453361 0.79 ALOX5 (0.58) ALOX5TAAR1NOTUMTSHRESR2
Hydrochloric Acid SCHEMBL31070804 0.78 ALOX5 (0.62) ALOX5TAAR1NOTUMTSHRESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
CN-222526051-U Electronic lock assembly and internal assembly for an electronic lock assembly 亚萨合莱美国住宅股份有限公司 2025-02-25 CN disclosed
CN-107629022-B Antibacterial synergist and preparation method and application thereof 上海医药工业研究院 2024-11-12 CN disclosed
CN-112640401-B Foldable device comprising an antenna 三星电子株式会社 2024-03-29 CN disclosed
CN-110870066-B Micro LED display and manufacturing method thereof 三星电子株式会社 2023-12-19 CN disclosed
CN-219939930-U Portable hair straightening comb with all-metal strip teeth 欧阳群 2023-11-03 CN disclosed
CN-219696748-U Connector, power module and electronic equipment 华为数字能源技术有限公司 2023-09-15 CN disclosed
CN-110396472-B Cassette for digital real-time PCR 光行科技株式会社 2023-07-25 CN disclosed
CN-110999557-B Method and apparatus for unloading IC units 洛克系统私人有限公司 2023-06-30 CN disclosed
CN-116322596-A System and method for controlling intelligent exercise recovery device and mitigating damage from vibration 海博艾斯公司 2023-06-23 CN disclosed
CN-115774495-A Touch display device and display panel 乐金显示有限公司 2023-03-10 CN disclosed
CN-115499999-A Printed circuit board interposer for radio frequency signal transmission 苹果公司 2022-12-20 CN disclosed
CN-112086827-B Compact coaxial cable connector for transmitting ultrahigh frequency signals 信思优有限责任公司 2022-12-13 CN disclosed
CN-115394736-A Vertical semiconductor device with side recess 西部数据技术公司 2022-11-25 CN disclosed
CN-114243362-A Feed-through device and signal conductor path arrangement ASML荷兰有限公司 2022-03-25 CN disclosed
CN-110716109-B Power distribution system 通用电气航空系统有限公司 2022-03-18 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed