SCHEMBL4454430

SCHEMBL4454430

Clc1cc(Cl)cc(-c2c(Cl)c(Cl)cc(Cl)c2Cl)c1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AHR P35869 8/20 0.55
ALDH1A1 P00352 3/20 0.53
CYP3A4 P08684 4/20 0.47
TSHR P16473 6/20 0.47
HSD17B10 Q99714 5/20 0.42
HPGD P15428 4/20 0.42
CASP1 P29466 1/20 0.41
MAPK1 P28482 1/20 0.38
TP53 P04637 1/20 0.36
CRHBP P24387 1/20 0.35
CRHR2 Q13324 1/20 0.35
RECQL P46063 1/20 0.35
CYP1B1 Q16678 1/20 0.35
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23827189 0.85 AHR (0.65) AHRALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL4449545 0.83 AHR (0.56) AHRALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL19991655 0.81 TSHR (0.53) AHRALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL463584 0.79 AHR (0.65) AHRALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL4452927 0.78 AHR (0.44) AHRALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL29369441 0.78 AHR (0.44) AHRALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL4453333 0.78 AHR (0.61) AHRALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL4452902 0.78 ALOX5 (0.45) AHRALDH1A1TSHRTP53
SCHEMBL4452692 0.77 CYP3A4 (0.64) AHRALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL4453597 0.75 AHR (0.68) AHRALDH1A1CYP3A4TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
US-20230330725-A1 VOLATILIZATION AND OXIDATION OF ORGANIC WASTE NATIONAL BANK OF CANADA (CA) 2023-10-19 US disclosed
CN-116075113-A Stacked SSD semiconductor device 西部数据技术公司 2023-05-05 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed