SCHEMBL4452946

SCHEMBL4452946

CCC(C)COC(=O)c1ccccc1C(=O)OCC(C)CC

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.70
ALDH1A1 P00352 5/20 0.70
MAPT P10636 1/20 0.60
CYP3A4 P08684 3/20 0.59
CA2 P00918 1/20 0.59
PRSS1 P07477 1/20 0.56
PRSS2 P07478 1/20 0.56
PRSS3 P35030 1/20 0.56
TDP1 Q9NUW8 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
TP53 P04637 1/20 0.51
MAPK1 P28482 1/20 0.51
LMNA P02545 2/20 0.50
HSD17B10 Q99714 1/20 0.47
ADRB2 P07550 3/20 0.47
ADRB1 P08588 3/20 0.47
ADRB3 P13945 3/20 0.47
NPC1 O15118 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11513723 0.95 ALDH1A1 (0.80) TSHRALDH1A1MAPTCYP3A4CA2
SCHEMBL27891835 0.93 MAPT (0.62) TSHRALDH1A1MAPTCYP3A4CA2
SCHEMBL1552226 0.90 LMNA (0.63) TSHRALDH1A1MAPTCYP3A4CA2
SCHEMBL29254280 0.90 TSHR (0.57) TSHRALDH1A1MAPTCYP3A4CA2
SCHEMBL16344862 0.89 ALDH1A1 (0.62) TSHRALDH1A1MAPTCYP3A4CA2
SCHEMBL11023805 0.89 ALDH1A1 (0.66) TSHRALDH1A1MAPTCYP3A4CA2
SCHEMBL14628671 0.87 TSHR (0.54) TSHRALDH1A1MAPTCYP3A4CA2
SCHEMBL28118089 0.86 ALDH1A1 (0.57) TSHRALDH1A1MAPTCYP3A4CA2
SCHEMBL27671307 0.86 SCN1A (0.57) TSHRALDH1A1MAPTCYP3A4CA2
SCHEMBL3684915 0.86 ALDH1A1 (0.66) TSHRALDH1A1MAPTCYP3A4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116199995-A High-fluidity polypropylene resin composition and molded article made from the same 韩华道达尔能源有限公司 2023-06-02 CN claimed
EP-4186931-A1 POLYPROPYLENE RESIN COMPOSITION WITH HIGH FLOWABILITY AND ARTICLE MOLDED THEREFROM Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2023-05-31 EP claimed
CN-118063652-A Process for producing propylene copolymers using catalyst systems with improved copolymerization activity 韩华道达尔能源有限公司 2024-05-24 CN disclosed
CN-117924563-A Solid catalyst for preparing polypropylene and method for preparing propylene derivative polymer 韩华道达尔能源有限公司 2024-04-26 CN disclosed
CN-116199995-A High-fluidity polypropylene resin composition and molded article made from the same 韩华道达尔能源有限公司 2023-06-02 CN disclosed
EP-4186931-A1 POLYPROPYLENE RESIN COMPOSITION WITH HIGH FLOWABILITY AND ARTICLE MOLDED THEREFROM Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2023-05-31 EP disclosed
CN-111349185-B Solid catalyst for propylene polymerization and method for producing block copolymer using the same 韩华道达尔能源有限公司 2023-02-03 CN disclosed
CN-108148153-B Solid catalyst and method for preparing propylene polymer or copolymer using the same 韩华道达尔有限公司 2021-08-10 CN disclosed
WO-2021118145-A1 METHOD FOR PREPARING OLEFIN-BASED POLYMER BY GAS-PHASE POLYMERIZATION 한화솔루션 주식회사 2021-06-17 WO disclosed
CN-111349185-A Solid catalyst for propylene polymerization and method for producing block copolymer using the same 韩华道达尔有限公司 2020-06-30 CN disclosed
CN-103189396-B The manufacture method of solid catalyst component for olefin polymerization, polymerization of olefines catalyst and olefin polymer 东邦钛株式会社 2016-06-29 CN disclosed
US-20150274870-A1 PERFLUOROALKYLENE ETHER-CONTAINING COMPOUND AND SURFACE PROTECTIVE FILM FUJI XEROX CO., LTD. (JP) 2015-10-01 US disclosed
CN-102918067-A Method for preparing spherical carrier for olefin polymerization catalyst, solid catalyst using same, and propylene polymer SAMSUNG TOTAL PETROCHEMICALS 2013-02-06 CN disclosed
US-20090281259-A1 CATALYST FOR PROPYLENE POLYMERIZATION AND THE METHOD OF PROPYLENE POLYMERIZATION USING THE CATALYST SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2009-11-12 US disclosed
EP-1805225-A1 CATALYST FOR PROPYLENE POLYMERIZATION AND THE METHOD OF PROPYLENE POLYMERIZATION USING THE CATALYST Samsung Total Petrochemicals Co. Ltd. (KR) 2007-07-11 EP disclosed
WO-2006062287-A1 CATALYST FOR PROPYLENE POLYMERIZATION AND THE METHOD OF PROPYLENE POLYMERIZATION USING THE CATALYST SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2006-06-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150274870-A1 PERFLUOROALKYLENE ETHER-CONTAINING COMPOUND AND SURFACE PROTECTIVE FILM F11, F12, F8 TSHR 249/4885ALDH1A1 2395/4885MAPT 4163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.