SCHEMBL4452979

SCHEMBL4452979

C=CC(=O)Nc1nc(NC(=O)C=C)nc(NC(=O)C=C)n1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 10/20 0.46
F13A1 P00488 1/20 0.43
LMNA P02545 1/20 0.43
TGM1 P22735 1/20 0.43
TGM3 Q08188 1/20 0.43
TSHR P16473 2/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
GSTO1 P78417 4/20 0.40
PTPN1 P18031 1/20 0.38
PTPN11 Q06124 1/20 0.38
EGFR P00533 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22356329 0.89 TGM2 (0.39) TGM2F13A1LMNATGM1TGM3
SCHEMBL8980546 0.84 TGM2 (0.39) TGM2F13A1LMNATGM1TGM3
SCHEMBL93702 0.84 TGM2 (0.39) TGM2F13A1LMNATGM1TGM3
Sulfuric Acid SCHEMBL5242393 0.78 TGM2 (0.37) TGM2F13A1LMNATGM1TGM3
SCHEMBL7641546 0.77 TGM2 (0.50) TGM2F13A1LMNATGM1TGM3
SCHEMBL20278582 0.75 EGFR (0.40) TGM2GSTO1EGFR
SCHEMBL5931306 0.75 TGM2 (0.44) TGM2F13A1LMNATGM1TGM3
SCHEMBL2828674 0.72 EGFR (0.51) TGM2PTPN1PTPN11EGFR
SCHEMBL28564782 0.72 TGM2 (0.52) TGM2F13A1LMNATGM1TGM3
Sulfuric Acid SCHEMBL5243123 0.71 NPC1 (0.44) TGM2F13A1LMNATGM1TGM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116322597-A Systems and methods for preservative removal in ophthalmic formulations 特清公司 2023-06-23 CN claimed
US-20070265365-A1 Water Soluble Polymers Containing Vinyl Unsaturation, Their Crosslinking and Process for Preparation Thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2007-11-15 US claimed
US-20230340348-A1 CO2-PHILIC CROSSLINKED POLYETHYLENE GLYCOL-BASED MEMBRANES FOR ACID AND SOUR GAS SEPARATIONS SAUDI ARABIAN OIL COMPANY (SA) 2023-10-26 US disclosed
US-20230340348-A1 CO2-PHILIC CROSSLINKED POLYETHYLENE GLYCOL-BASED MEMBRANES FOR ACID AND SOUR GAS SEPARATIONS SAUDI ARABIAN OIL COMPANY (SA) 2023-10-26 US disclosed
US-11718805-B2 CO2-philic crosslinked polyethylene glycol-based membranes for acid and sour gas separations SAUDI ARABIAN OIL COMPANY (SA) 2023-08-08 US disclosed
US-11718805-B2 CO2-philic crosslinked polyethylene glycol-based membranes for acid and sour gas separations SAUDI ARABIAN OIL COMPANY (SA) 2023-08-08 US disclosed
CN-116322597-A Systems and methods for preservative removal in ophthalmic formulations 特清公司 2023-06-23 CN disclosed
CN-110023380-B Aqueous dispersions of polyolefin supramolecular polymers and their use in cosmetics 莱雅公司 2022-10-04 CN disclosed
CN-110494122-B Process for dyeing hair comprising pigment and supramolecular polymer aqueous dispersion 莱雅公司 2022-09-27 CN disclosed
US-20220213399-A1 CO2-PHILIC CROSSLINKED POLYETHYLENE GLYCOL-BASED MEMBRANES FOR ACID AND SOUR GAS SEPARATIONS SAUDI ARABIAN OIL COMPANY (SA) 2022-07-07 US disclosed
WO-2022147579-A1 CO2-PHILIC CROSSLINKED POLYETHYLENE GLYCOL-BASED MEMBRANES FOR ACID AND SOUR GAS SEPARATIONS SAUDI ARABIAN OIL COMPANY (SA) 2022-07-07 WO disclosed
US-20060094844-A1 Inclusion complexes of unsaturated monomers, their polymers and process for preparation thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2006-05-04 US disclosed
EP-0013267-B1 METHOD OF MAKING LAMINATED PRODUCTS Österreichisches Forschungszentrum Seibersdorf Ges.m.b.H. (AT) 1982-06-23 EP disclosed
US-4246369-A POWDER COATINGS AND ELECTROCOATINGS SCM CORPORATION (US) 1981-01-20 US disclosed
US-4204932-A POWDER COATING SCM CORPORATION (US) 1980-05-27 US disclosed
US-4133916-A Coating process with compositions of active hydrogen compound, unsaturated or epoxy compound, and carbamothioate curing agent SCM CORPORATION (US) 1979-01-09 US disclosed
US-4130522-A Aqueous coating composition and process SCM CORPORATION (US) 1978-12-19 US disclosed
US-4070258-A Dual cure cathodic electrocoating compositions SCM CORPORATION (US) 1978-01-24 US disclosed
US-4035273-A Cathodic electrocoating process SCM CORPORATION (US) 1977-07-12 US disclosed
US-4035274-A Dual cure cathodic electrocoating SCM CORPORATION (US) 1977-07-12 US disclosed