Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TGM2 | P21980 | 8/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TGM1 | P22735 | 5/20 | 0.41 |
| ▸ | F13A1 | P00488 | 4/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7641546 | 0.92 | TGM2 (0.50) | NPC1RAB9ASMN1; SMN2LMNATGM2 | |
| SCHEMBL5931306 | 0.75 | TGM2 (0.44) | LMNATGM2PTPN1PTPN11EGFR | |
| SCHEMBL29277100 | 0.74 | L3MBTL1 (0.68) | HTTHPGD | |
| Pyrimidine SCHEMBL4456823 | 0.74 | BTK (0.36) | TGM2PTPN1PTPN11EGFRTGM1 | |
| Sulfuric Acid SCHEMBL5244029 | 0.74 | MAPK3 (0.41) | TGM2PTPN1PTPN11EGFRTGM1 | |
| Sulfuric Acid SCHEMBL5242393 | 0.73 | TGM2 (0.37) | LMNATGM2EGFRTGM1F13A1 | |
| Sulfuric Acid SCHEMBL5242033 | 0.73 | HTT (0.49) | NPC1RAB9ALMNAHTTHPGD | |
| Sulfuric Acid SCHEMBL10783007 | 0.72 | TGM2 (0.85) | SMN1; SMN2LMNATGM2EGFRTGM1 | |
| SCHEMBL28564782 | 0.72 | TGM2 (0.52) | NPC1LMNATGM2PTPN1PTPN11 | |
| Sulfuric Acid SCHEMBL4458775 | 0.71 | EGFR (0.41) | TGM2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828253-A1 | INCLUSION COMPLEXES OF UNSATURATED MONOMERS, THEIR POLYMERS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-09-05 | — | — | EP | claimed |
| EP-1828255-A1 | WATER SOLUBLE POLYMERS CONTAINING VINYL UNSATURATION, THEIR CROSSLINKING AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-09-05 | — | — | EP | claimed |
| WO-2006046254-A1 | WATER SOLUBLE POLYMERS CONTAINING VINYL UNSATURATION, THEIR CROSSLINKING AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-05-04 | — | — | WO | claimed |
| WO-2006046255-A1 | INCLUSION COMPLEXES OF UNSATURATED MONOMERS, THEIR POLYMERS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-05-04 | — | — | WO | claimed |
| EP-1828253-A1 | INCLUSION COMPLEXES OF UNSATURATED MONOMERS, THEIR POLYMERS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-09-05 | — | — | EP | disclosed |
| EP-1828255-A1 | WATER SOLUBLE POLYMERS CONTAINING VINYL UNSATURATION, THEIR CROSSLINKING AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006046254-A1 | WATER SOLUBLE POLYMERS CONTAINING VINYL UNSATURATION, THEIR CROSSLINKING AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-05-04 | — | — | WO | disclosed |
| WO-2006046255-A1 | INCLUSION COMPLEXES OF UNSATURATED MONOMERS, THEIR POLYMERS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-05-04 | — | — | WO | disclosed |