SCHEMBL8980546

SCHEMBL8980546

C=CC(=O)Nc1nc(S)nc(S)n1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 9/20 0.39
▸ F13A1 P00488 1/20 0.37
▸ LMNA P02545 1/20 0.37
▸ TGM1 P22735 1/20 0.37
▸ TGM3 Q08188 1/20 0.37
▸ GSTO1 P78417 5/20 0.35
▸ ALDH1A1 P00352 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ PTPN1 P18031 1/20 0.33
▸ PTPN11 Q06124 1/20 0.33
▸ EGFR P00533 2/20 0.33
▸ ITK Q08881 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4452979 0.84 TGM2 (0.46) TGM2F13A1LMNATGM1TGM3
SCHEMBL22356329 0.75 TGM2 (0.39) TGM2F13A1LMNATGM1TGM3
SCHEMBL93702 0.75 TGM2 (0.39) TGM2F13A1LMNATGM1TGM3
SCHEMBL14093857 0.70 CA2 (0.31) —
Sulfuric Acid SCHEMBL5242393 0.69 TGM2 (0.37) TGM2F13A1LMNATGM1TGM3
SCHEMBL7641546 0.68 TGM2 (0.50) TGM2F13A1LMNATGM1TGM3
SCHEMBL20278582 0.67 EGFR (0.40) TGM2GSTO1EGFRITK
SCHEMBL5931306 0.67 TGM2 (0.44) TGM2F13A1LMNATGM1TGM3
SCHEMBL2828674 0.64 EGFR (0.51) TGM2PTPN1PTPN11EGFRITK
SCHEMBL28564782 0.64 TGM2 (0.52) TGM2F13A1LMNATGM1TGM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5569545-A LAMINATE HAVING COPPER FOIL WITH METAL ALLOY LAYER ON SIDE TO BE BONDED WITH INSULATING LAYER, SAID LAYERS BEING CROSSLINKED WITH EACH OTHER BY SULFUR BONDS NIPPON DENKAI LTD. (JP) 1996-10-29 — — US disclosed
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