SCHEMBL4453201

SCHEMBL4453201

O=C(O)CCOc1nc(OCCC(=O)O)nc(OCCC(=O)O)n1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RXRA P19793 16/20 0.45
RXRB P28702 15/20 0.45
RXRG P48443 10/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
LMNA P02545 1/20 0.42
MCL1 Q07820 1/20 0.41
PPARG P37231 1/20 0.40
PPARD Q03181 1/20 0.40
PPARA Q07869 1/20 0.40
MMP2 P08253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3260741 0.79 LMNA (0.47) RXRARXRBRXRGL3MBTL1LMNA
SCHEMBL24937308 0.67 L3MBTL1 (0.61) L3MBTL1LMNAMCL1PPARAMMP2
SCHEMBL11573013 0.67 MCL1 (0.52) RXRARXRBRXRGL3MBTL1LMNA
SCHEMBL375634 0.66 LMNA (0.53) L3MBTL1LMNA
SCHEMBL1766162 0.64 LMNA (0.50) L3MBTL1LMNA
SCHEMBL958817 0.64 LMNA (0.50) L3MBTL1LMNA
SCHEMBL1766170 0.64 LMNA (0.50) L3MBTL1LMNA
SCHEMBL22771166 0.64 LMNA (0.50) L3MBTL1LMNA
SCHEMBL2759396 0.64
SCHEMBL16134189 0.64 LMNA (0.50) L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8476377-B2 Crosslinkable polyamide molding compounds and molded parts produced therewith EMS—Patent AG (CH) 2013-07-02 US disclosed
US-20090171038-A1 CROSSLINKABLE POLYAMIDE MOLDING COMPOUNDS AND MOLDED PARTS PRODUCED THEREWITH EMS-PATENT AG (CH) 2009-07-02 US disclosed
EP-0007114-B1 AROMATIC POLYAMIDE FILM AND PROCESS FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 1983-03-16 EP disclosed
US-4291142-A Crosslinked aromatic polyamide film and process for producing the same TEIJIN, LIMITED (JP) 1981-09-22 US disclosed
EP-0007114-A1 Aromatic polyamide film and process for producing the same TEIJIN LIMITED (JP) 1980-01-23 EP disclosed