SCHEMBL4453337

SCHEMBL4453337

Clc1cccc(-c2ccc(Cl)c(Cl)c2Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 0.61
TDO2 P48775 1/20 0.43
ALOX5 P09917 1/20 0.42
DHFR P00374 1/20 0.42
TAAR1 Q96RJ0 1/20 0.41
PDK2 Q15119 1/20 0.41
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
NUDT1 P36639 1/20 0.39
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.39
ESR2 Q92731 1/20 0.39
NOTUM Q6P988 1/20 0.39
NPC1 O15118 1/20 0.39
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39
NFKB1 P19838 1/20 0.39
RAB9A P51151 1/20 0.39
NFKB2 Q00653 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4445051 0.85 TDO2 (0.44) AHRTDO2ALOX5DHFRTAAR1
SCHEMBL4445043 0.83 AHR (0.61) AHRTDO2ALOX5DHFRTAAR1
SCHEMBL29377957 0.83 AHR (0.61) AHRTDO2ALOX5DHFRTAAR1
SCHEMBL4456555 0.80 AHR (0.71) AHRPDK2TP53TSHR
SCHEMBL2466769 0.80 AHR (0.57) AHRTAAR1PDK2ESR2NOTUM
SCHEMBL3269842 0.78 TDO2 (0.46) AHRTDO2ALOX5DHFRTAAR1
SCHEMBL2235302 0.78 AHR (0.59) AHRTDO2ALOX5DHFRTAAR1
SCHEMBL29983843 0.78 AHR (0.60) AHRALOX5
SCHEMBL381602 0.78 AHR (0.60) AHRALOX5
SCHEMBL9486784 0.77 ALOX5 (0.53) AHRTDO2ALOX5DHFRTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
WO-2025130770-A1 ELECTRONIC DEVICE 维沃移动通信有限公司 2025-06-26 WO disclosed
CN-117525843-A Electronic equipment 维沃移动通信有限公司 2024-02-06 CN disclosed
CN-106799952-B Control method and device of vehicle-mounted air purifier 杭州联络互动信息科技股份有限公司 2024-01-16 CN disclosed
US-20230330725-A1 VOLATILIZATION AND OXIDATION OF ORGANIC WASTE NATIONAL BANK OF CANADA (CA) 2023-10-19 US disclosed
CN-110607279-B 3D culture system of primary tumor cells, and culture method and application thereof 深圳优圣康医学检验实验室 2023-09-19 CN disclosed
CN-113208502-B Cleaning device LG电子株式会社 2023-08-04 CN disclosed
CN-116234161-A Circuit board and computing device 超聚变数字技术有限公司 2023-06-06 CN disclosed
CN-115378394-A Transformer-based wideband filter with ripple reduction 苹果公司 2022-11-22 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed